Quantum Healthy Longevity for healthy people, planet, and growth

Woods, Tina; Palmarini, Nic; Corner, Lynne; Barzilai, Nir; Bethell, Lord James; Cox, Lynne S.; Eyre, Harris A.; Ferrucci, Luigi; Fried, Linda P.; Furman, David; Kennedy, Brian K.; Roddam, Andrew; Scott, Andrew; Siow, Richard

doi:10.1016/s2666-7568(22)00267-7

Cited by 5 publications

(2 citation statements)

References 10 publications

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“…Tina Woods introduced the concept of the exposome, which refers to the sum total of exposures that influence human health. By addressing these interacting lifestyle factors, such as diet and physical activity; socioeconomic determinants, such as discrimination, early and lifelong education, training and skills, financial status, and social support; and, increasingly, the characteristics of physical environments, such as green spaces and air quality, we can mitigate systemic chronic inflammation and promote lifelong health ( Woods et al, 2022 ). This comprehensive strategy necessitates the integration of science, technology, policy, regulatory reforms, public engagement, and private sector investment to advance the mission of healthy longevity.…”

Section: Innovation In the Broader Longevity Domainmentioning

confidence: 99%

The Longevity Med Summit: insights on healthspan from cell to society

Falshaw,

Sagner,

Siow

2024

Front. Aging

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In recent years, there has been a paradigm shift with regards to ageing, challenging its traditional perception as an inevitable and natural process. Researchers have collectively identified hallmarks of ageing, nine of which were initially proposed in 2013 and expanded in 2023 to include disabled macroautophagy, chronic inflammation, and dysbiosis, enhancing our understanding of the ageing process at microscopic, cellular, and system-wide levels. Strategies to manipulate these hallmarks present opportunities for slowing, preventing, or reversing age-related diseases, thereby promoting longevity. The interdependence of these hallmarks underscores the necessity of a comprehensive, systems-based approach to address the complex processes contributing to ageing. As a primary risk factor for various diseases, ageing diminishes healthspan, leading to extended periods of compromised health and multiple age-related conditions towards the end of life. The significant gap between healthspan and lifespan holds substantial economic and societal implications. The inaugural Longevity Med Summit (4–5 May 2023, Cascais, Portugal) provided an international forum to discuss the academic and industry landscape of healthy longevity research, preventive medicine and clinical practice to enhance healthspan.

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Section: Innovation In the Broader Longevity Domainmentioning

confidence: 99%

The Longevity Med Summit: insights on healthspan from cell to society

Falshaw,

Sagner,

Siow

2024

Front. Aging

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“…Ultimately, innovations in healthy aging research should be relevant and have a tangible impact on people's lives. Building a comprehensive knowledge base on healthy aging is a collective effort that involves contributions from every country and offers opportunities for cross-learning [33].…”

Section: Main Directions For Future Researchmentioning

confidence: 99%

Aging and Geriatric Care: A Global Imperative Towards Universal Health Coverage

Singh,

Yadav,

Doskaliuk

2023

AAEE

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The global population of older people is projected to surpass the number of children under 5 years old and adolescents by 2050, with developing countries housing the majority of older individuals. This demographic shift necessitates adjustments in global health systems to cater to the increasing demand for age-appropriate care. Gerontology, as an interdisciplinary field, encompasses the study of biological, social, and medical aspects of aging. Anti-aging, a distinct discipline, focuses on understanding and combatting age-related ailments. This review provides insights into the distinctive aspects of anti-aging research, highlights current priority issues in health promotion and anti-aging measures, and explores implications of crises on aging research and healthcare. Furthermore, it emphasizes the need for collaboration among interdisciplinary research networks, integration of science and technology, and the involvement of key stakeholders to ensure universal health coverage. Future research should address the multidimensional aspects of healthy aging, reflect research priorities and preferences of older individuals, and promote health equity. This collective effort will contribute to the development of innovative solutions and facilitate cross-learning among countries to enhance the well-being of aging populations globally.

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Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

Lyu,

Fu,

Wilczok

et al. 2024

Aging

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The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan.

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Quantum Healthy Longevity for healthy people, planet, and growth

Cited by 5 publications

References 10 publications

The Longevity Med Summit: insights on healthspan from cell to society

The Longevity Med Summit: insights on healthspan from cell to society

Aging and Geriatric Care: A Global Imperative Towards Universal Health Coverage

Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

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