Sex and sexuality are fundamental aspects of what it is to be human, but they have been ignored or neglected by museums historically. Some institutions transferred sexually graphic material to secret museums during the 19th and 20th centuries, recognising its importance and preserving it, but denying public access to it. Other museums did not collect relevant material at all. Museums have now begun to respond to significant changes in society and acknowledge sex and sexuality more directly, but traditional approaches impose limitations. This paper focuses on a small number of recent projects that have addressed sexuality through alternative approaches to objects, collections and narratives. Collectively, these raise bigger philosophical questions of intention, audience and impact. Some institutions, including the British Museum (A History of the World in 100 objects) and the UK's National Portrait Gallery (Family Album), have addressed alternative sexualities as an integrated part of broader projects or touring exhibitions that have been aimed at a wide audience. The temporary queering of Birmingham Museum and Art Gallery (Queering the Museum) and the National Museum in Warsaw, Poland (Ars Homo Erotica) are representative examples of an alternative approach that impacts a wider audience, but arguably, in different ways for Lesbian, gay, bisexual and transgender (LGBT) and non‐LGBT publics. Museums have a duty to represent the past and present accurately and meaningfully for future generations, and this includes acknowledging histories of sex and sexuality. Although the projects discussed here adopt different approaches, they all demonstrate the potential for museums to use their collections to help generate greater awareness and acceptance of diversity in sexuality, and a more inclusive and tolerant society.