Quercetin triglycoside from Capparis spinosa

Genotoxic and Antimutagenic Effects ofCapparis spinosaL. on theAllium cepaL. Root Tip Meristem Cells

“…Preliminary phytochemistry studies revealed the presence of lipids, alkaloids, glucocapperin as major glucosinolate, and a number of antioxidant phytochemicals such as flavonoids and other polyphenols in C. spinosa (Rodrigo et al 1992;Sharaf et al, 2000;Germanò et al 2002). Furthermore, Quercetin-3-rutinoside (rutin) has appeared to be common to most species and varieties, as well as the most abundant flavonoid in CS (Sharaf et al 2000., Bonina et al 2002Germanò et al 2002). Recently, Çaliş et al(1999, 2002) have isolated from mature fruits of CS two glucosecontaining 1H-indole 3-acetonitrile compounds, capparilosides A and B and two (6S)-hydroxy-3-oxo-α-ionol glucosides, corchoinoside c and a phenyl glucuside.…”

“…Furthermore, in vitro chondroprotective effects of the lyophi-lized methanolic extract from flowering buds of CS on human chondrocytes stimulated by pro-inflammatory cytokine Interleukin-1β (IL-1β) were suggested. The plants extracts studied have been reported to contain lipids, alkaloids, glucocapperin as major glucosinolate, and a number of antioxidant phytochemicals such as flavonoids andotherpolyphenols (Rodrigo et al 1992;Sharaf et al, 2000;Germanò et al 2002). Quercetin-3-rutinoside (rutin) has appeared to be common to most species and varieties, as well as the most abundant flavonoid (Sharaf et al 2000;Bonina et al 2002;Germanò et al 2002) and several quercetin and kaempferol glycosides, as well as of hydroxycinnamic acids, has also been demonstrated (Bonina et al 2002) in C. spinosa.…”

“…Previous chemical studies on Capparis spinosa (CS) showed that raw flower buds contain lipids, alkaloids, glucocapperin as major glucosinolate, and a number of antioxidant phytochemicals such as flavonoids andotherpolyphenols (Rodrigo et al 1992;Sharaf et al 2000;Germanò, et al 2002.). Quercetin-3-rutinoside (rutin) has appeared to be common to most species and varieties, as well as the most abundant flavonoid in CS (Sharaf et al 2000;Bonina et al 2002;Germanò et al 2002).…”

“…Quercetin-3-rutinoside (rutin) has appeared to be common to most species and varieties, as well as the most abundant flavonoid in CS (Sharaf et al 2000;Bonina et al 2002;Germanò et al 2002). Recently, Çaliş et al(1999, 2002) have isolated from mature fruits of CS two glucose-containing 1H-indole 3-acetonitrile compounds, capparilosides A and B and two (6S)-hydroxy-3-oxo-α-ionol glucosides, corchoinoside c and a phenyl glucuside.…”

Inhibition of Aldose Reductase and Red Blood Cell Sorbitol Accumulation by Extract of Capparis spinosa

“…In traditional medicine, this plant is used as a diuretic and as way a treatment for gout, rheumatism and liver disease. Different studies have reported the analgesic, anti-hepatotoxic, anti-allergic, and hypoglycemic, hypolipidemic and anti-allergic effects (12)(13)(14)(15)(16)(17).…”