Questions and Answers in Pain Medicine

Suer, Michael; Sehgal, Nalini

doi:10.1007/978-3-030-68204-0

Cited by 2 publications

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“…Acute postoperative pain is common among amputees, 1 and is associated with chronic residual and phantom limb pain. 2 Long-term pain after amputation can have significant negative consequences, including depression, 3 disability, 4 unemployment 5 and poorer health-related quality of life.…”

Section: Introductionmentioning

confidence: 99%

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

et al. 2021

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ObjectivesTo explore patient experiences, understanding and perceptions of analgesia following major lower limb amputation.DesignQualitative interview study, conducted as part of a randomised controlled feasibility trial.SettingParticipants were recruited from two general hospitals in South Wales.ParticipantsInterview participants were patients enrolled in PLACEMENT (Perineural Local Anaesthetic Catheter aftEr Major lowEr limb amputatioN Trial): a randomised controlled feasibility trial comparing the use of perineural catheter (PNC) versus standard care for postoperative pain relief following major lower limb amputation. PLACEMENT participants who completed 5-day postoperative follow-up, were able and willing to participate in a face-to-face interview, and had consented to be contacted, were eligible to take part in the qualitative study. A total of 20 interviews were conducted with 14 participants: 10 male and 4 female.MethodsSemi-structured, face-to-face interviews were conducted with participants over two time points: (1) up to 1 month and (2) at least 6 months following amputation. Interviews were audio-recorded, transcribed verbatim and analysed using a framework approach.ResultsInterviews revealed unanticipated benefits of PNC usage for postoperative pain relief. Participants valued the localised and continuous nature of this mode of analgesia in comparison to opioids. Concerns about opioid dependence and side effects of pain relief medication were raised by participants in both treatment groups, with some reporting trying to limit their intake of analgesics.ConclusionsFindings suggest routine placement of a PNC following major lower limb amputation could reduce postoperative pain, particularly for patient groups at risk of postoperative delirium. This method of analgesic delivery also has the potential to reduce preoperative anxiety, alleviate the burden of pain management and minimise opioid use. Future research could further examine the comparison between patient-controlled analgesia and continuous analgesia in relation to patient anxiety and satisfaction with pain management.Trial registration numberISRCTN: 85710690; EudraCT: 2016-003544-37.

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Section: Introductionmentioning

confidence: 99%

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

et al. 2021

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Diffuse Idiopathic Skeletal Hyperostosis (DISH): Palaeopathological Study on Human Remains from Parthian Cemetery, Liyarsangbon, Guilan, Iran; With a Special Reference to Metastatic Cancer as the Cause of Death

Eghdami,

Roudbordeh,

Omami

et al. 2024

Preprint

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Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a systemic noninflammatory condition that is characterized by unknown causes. It is closely associated with various factors including sex, age, environmental influences, genetic predisposition, and fluctuations in medication. Certain diseases, including gout, metabolic disorders such as type 2 diabetes as well as populations. Paleopathological studies of ancient remains indicate that it has been identified in various archaeological populations. The studied individual was discovered from Liyarsangbon cemetery, Amlash city, Guilan province, Iran. On the base of preliminary typology, the artifacts and grave types, the site was dated to the Parthian (247 BCE–224 CE) and in a few cases to the Sassanid period (224–651 CE). The remains of an individual with a potential case of DISH disease have attracted the interest of researchers. While there are other possible diagnoses such as spondyloarthropathies, Paget's disease, metabolic diseases, and POEMS syndrome. Following osteological examinations, advanced radiological imaging methods, in addition to visual inspection, were employed to differentiate between potential diagnoses. Based on criteria, the ultimate diagnosis was determined to be either DISH or eDISH. The presence of patchy sclerotic bone lesions in the majority of the pelvic, and spine, suggesting osteoblastic metastatic tumors that may have contributed to the individual's demise.

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Questions and Answers in Pain Medicine

Cited by 2 publications

References 0 publications

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

Diffuse Idiopathic Skeletal Hyperostosis (DISH): Palaeopathological Study on Human Remains from Parthian Cemetery, Liyarsangbon, Guilan, Iran; With a Special Reference to Metastatic Cancer as the Cause of Death

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