2021
DOI: 10.1016/j.rechem.2021.100135
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Quick synthesis of isatin-derived knoevenagel adducts using only eco-friendly solvent

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Cited by 6 publications
(1 citation statement)
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“…The synthesis of starting materials such as isatylidene malononitrile 27 and isatylidene cyanoacetate 28 was performed using a known method. We carried out a reaction using the mono-halogenated derivatives of isatylidene malononitrile at 5-fluoro, 5-chloro, 5-bromo, 5-iodo and 7-fluoro positions; all these substrates gave the desired products with yields in the range of 86–92% (Table 2, 2b–2f ).…”
Section: Resultsmentioning
confidence: 99%
“…The synthesis of starting materials such as isatylidene malononitrile 27 and isatylidene cyanoacetate 28 was performed using a known method. We carried out a reaction using the mono-halogenated derivatives of isatylidene malononitrile at 5-fluoro, 5-chloro, 5-bromo, 5-iodo and 7-fluoro positions; all these substrates gave the desired products with yields in the range of 86–92% (Table 2, 2b–2f ).…”
Section: Resultsmentioning
confidence: 99%