2024
DOI: 10.1101/2024.08.27.609919
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QuICSeedR: An R package for analyzing fluorophore-assisted seed amplification assay data

Manci Li,
Damani N. Bryant,
Sarah Gresh
et al.

Abstract: SummaryFluorophore-assisted seed amplification assays (F-SAAs), such as real-time quaking-induced conversion (RT-QuIC) and fluorophore-assisted protein misfolding cyclic amplification (F-PMCA), have become indispensable tools for studying protein misfolding in neurodegenerative diseases. However, analyzing data generated by these techniques often requires complex and time-consuming manual processes. Additionally, the lack of standardization in F-SAA data analysis presents a significant challenge to the interpr… Show more

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