Quinazoline addition to indole hydrazone derivatives in TFA as a facile synthesis of trifluoroacetylhydrazide quinazoline σ-adducts

New pathways for the synthesis of indolyl-containing quinazoline trifluoroacetohydrazides

“…We previously described that heating of quinazoline 4 with hydrazones 3a-c in TFA resulted in the formation of products 5a-c (Scheme 2) [14].…”