Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification

Efficient Synthesis of RuO2 Nanoparticle with excellent activity for one‐pot Synthesis of 2,3‐disubstituted quinazolin‐4(1H)‐ones

“…Among nitrogen heterocycles, quinazolinones have drawn the attention of chemists and medicinal chemistry because of their various biological activities (figure 1). [1,2] Regarding the variety of uses of quinazolinones and their analogs in medicinal chemistry, various methods to synthesize these compounds have been developed. The various synthetic strategies (Scheme 1) [3][4][5][6][7][8] adopted for the generation of 2,3-disubstituted quinazolin-4(1H)-ones can be classified in the following routes.…”

Design, synthesis, and anticancer activities of sodium quinazolin‐4‐diselenide compounds

“…As a series of small‐molecule drugs with good biological activities, quinazoline compounds caused much attention and deeply studied by many chemical workers, widely used in medicals and pesticides area in recent years. We were particularly interested in 4‐substituted quinazolines, which atom was replaced with O, N, S, and Se (Figure ) .…”

Synthesis of some novel quinazolin‐4(3H)‐one hybrid molecules as potent urease inhibitors

“…In recent years, considerable evidence has been found on the importance of quinazolinone derivatives in the pharmaceutical chemistry . For example, they have attracted attention as an important nucleus in the class of therapeutic agents because of their wide range of biological activities .…”