Quincke’s Disease Presenting After Cocaine Exposure

Abstract

Quincke's disease is a very rare form of upper airway angioedema, and it is characterized by a well-localized edematous reaction. Its epidemiology is not documented due to the rarity of this condition. Causes include allergic reactions, infectious diseases, and trauma, among others. This article describes a rare case of a 27-year-old man who presented to the Emergency Department with isolated uvular edema associated with cocaine exposure.

Recurrent Isolated Uvular Angioedema Associated With Intranasal Cocaine Use: A Case Report

“…In our case, isolated uvular angioedema developed in the setting of cocaine use on multiple occasions, supporting the role of cocaine as the likely trigger. Literature reports cases of angioedema due to the irritant effects of inhaled cannabis and cocaine [2][3][4][5][6].…”

The Price of a Life: Unveiling the Struggle of Living With Hereditary Angioedema

“…Another notable aspect of this case is the patient's history of cocaine use and the urine drug screen that was positive for cocaine. Several cases of Quincke’s Disease (isolated angioedema of the uvula) induced by cocaine use have been documented [ 8 - 11 ], though to the authors' knowledge, none of the patients were subsequently diagnosed with HAE. Though HAE was not diagnosed, cocaine-induced angioedema in these patients lends support to the hypothesis that cocaine could be a potential angioedema trigger in our patient.…”