1974
DOI: 10.1159/000136501
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Quingestanol Acetate Metabolism in Women

Abstract: Quingestanol acetate was absorbed rapidly and showed a high order of bioavailability after oral administration to women. The composition of the radioactive steroids in the plasma of the subjects suggests that the initial biotransformation of the drug involves two pathways, namely, deacylation to quingestanol and O-dealkylation to norethindrone acetate, and that both of these metabolites are subsequently converted to norethindrone.

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