Quinoline-Based Polyazaheterocycles by a Hydrogen Peroxide-Mediated Isocyanide Insertion

Bandehali-Naeini, Farzaneh; Shiri, Morteza; Ramezani, Bahareh; Rajai‐Daryasarei, Saideh

doi:10.1080/10406638.2019.1599403

Cited by 4 publications

(1 citation statement)

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“…Farzaneh Bandehali‐Naeini et al . developed efficient and environment friendly method of synthesis of quinoline based polyazaheterocycles thiazino[3,4‐a]quinazolin‐15(6H)‐one (121) by reacting 2‐(2‐mercaptoquinolin‐3‐yl)‐2,3‐dihydroquinazolin‐4(1H)‐one (119) and cyclohexylisocyanide (120) in the presence of Hydrogen peroxide with solvent THF at 50 °C for 2 h [41] . (Scheme 23 )…”

Section: Introductionmentioning

confidence: 99%

Chemistry of Quinoline Based Heterocycle Scaffolds: A Comprehensive Review

et al. 2022

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Quinoline is a significant scaffold among heterocyclic compounds and can be used as a key building block for the development of novel medications. Quinoline and its derivatives are recognised as biologically active substances with a number of pharmacological properties. Nowadays, quinolinebased heterocycle scaffolds have achieved a prominent position in medicinal chemistry due to their significant pharmaco-logical and biological properties. The discovery and creation of cutting-edge medications to treat a variety of diseases is an example of the usefulness of these compounds. The current study outlines the range of methods available to create different quinolone-based heterocycle scaffolds and their advantageous therapeutic applications using the literature that has been published up to 2022.

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Section: Introductionmentioning

confidence: 99%

Chemistry of Quinoline Based Heterocycle Scaffolds: A Comprehensive Review

et al. 2022

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Novel probe based on rhodamine B and quinoline as a naked-eye colorimetric probe for dual detection of nickel and hypochlorite ions

Hooshmand,

Baeiszadeh,

Mohammadnejad

et al. 2023

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This work demonstrates the design and straightforward syntheses of several novel probe-based on rhodamine B and 2-mercaptoquinoline-3-carbaldehydes as a naked-eye colorimetric probe, indicating a sensitive and selective recognition towards nickel (II) with a limit of detection 0.30 μmol L−1 (0.02 mg L−1). Further, by employing the oxidation property of hypochlorite (OCl−), this novel probe parallelly has been deployed to detect hypochlorite in laboratory conditions with a limit of detection of 0.19 μmol mL−1 and in living cells. Regarded to negligible cell toxicity toward mammalian cells, this probe has the potential to determine these analytes in in-vivo investigation and foodstuff samples.

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Recent Advances on Diversity Oriented Heterocycle Synthesis of Fused Quinolines and Its Biological Evaluation

Abass

Alzandi

Hassan

et al. 2020

Polycyclic Aromatic Compounds

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Quinoline-Based Polyazaheterocycles by a Hydrogen Peroxide-Mediated Isocyanide Insertion

Abstract: An efficient and green protocol for the synthesis of quinoline-based polyazaheterocycles with 2-(2-mercaptoquinolin-3-yl)-2,3-dihydroquinazolin4(1H)-ones and aliphatic and aromatic isocyanides using hydrogen peroxide is described.

Cited by 4 publications

References 27 publications

Chemistry of Quinoline Based Heterocycle Scaffolds: A Comprehensive Review

Chemistry of Quinoline Based Heterocycle Scaffolds: A Comprehensive Review

Novel probe based on rhodamine B and quinoline as a naked-eye colorimetric probe for dual detection of nickel and hypochlorite ions

Recent Advances on Diversity Oriented Heterocycle Synthesis of Fused Quinolines and Its Biological Evaluation

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