Quinolone Allergy?

Landor, Michael; Waxman, Jennie

doi:10.1016/s1081-1206(10)63319-4

Cited by 8 publications

(2 citation statements)

References 21 publications

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“…It is still unclear whether this hematologic effect may be connected to the skin reaction. Interestingly, other antibiotics, such as ciprofloxacin, have been also reported to produce skin disorders, concurrently with severe neutropenia (7,8). Bullous skin lesions have been described in association with a variety of drugs (7), but the mechanism of skin adverse reaction is still unclear.…”

Section: Discussionmentioning

confidence: 99%

Nafcillin-Induced Bullous Skin Eruption with Granulocytopenia in a Patient with End-Stage Renal Disease

et al. 2012

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Nafcillin is an antibiotic used for infections due to penicillin-resistant Staphylococcus aureus. In general, the adverse reactions to nafcillin have not been frequent and serious. We report here a new type of adverse reaction to nafcillin in a patient with end-stage renal disease in whom nafcillin caused the unexpected complication of bullous drug eruption and subseqent neutropenia. Three weeks after the start of intravenous nafcillin for the treatment of peritoneal dialysis peritonitis, the patient developed blisters on his right ankle. These became progressive and widespread, with bullae affecting most of the body surface. In addition, neutropenia developed three days after the appearance of bullous skin lesions. Spontaneous recovery of skin lesions and neutropenia was observed after the withdrawal of naficillin. When treating patients with chronic renal failure, physicians should be aware of these rare but potentially severe adverse reactions.

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Section: Discussionmentioning

confidence: 99%

Nafcillin-Induced Bullous Skin Eruption with Granulocytopenia in a Patient with End-Stage Renal Disease

et al. 2012

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“…Известно, что плацента не является препятстви ем для поступления материнских AT класса IgG к плоду [19]. Трансплацентарный перенос материн ских AT, идущий за счет активных энергозависимых механизмов, обеспечивает избыточную "перекачку" и накопление материнских AT в организме плода (даже против градиентов концентраций) [19]. Эпи зодическое или постоянное повышение уровня ан тиинсулиновых ATI класса IgG выявляется у 92% беременных с СД 1 типа.…”

Section: диабетическая фетопатияunclassified

Autoantitela k insulinu, sakharnyy diabet 1 tipa i diabeticheskaya nefropatiya

Poletaev¹,

Полетаев²,

Bulykina³

et al. 2000

Diabetes mellitus

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Skin manifestations of drug reactions

Rosso

2002

Curr Allergy Asthma Rep

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Dermatologic manifestations of adverse drug reactions are commonly encountered in both hospital-based and ambulatory medical practice. Diagnosis is confounded by the myriad clinical presentations associated with cutaneous drug eruptions. Some presentations are highly characteristic, while others are not as straightforward, and may simulate other primary dermatoses. In many cases, patients are utilizing several medications and an obvious temporal relationship to a specific drug is not always apparent or expressed by the patient during disclosure of his or her medical history. A thorough medication history and a high index of suspicion are very important components in the diagnosis of drug eruptions.

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Quinolone Allergy?

Cited by 8 publications

References 21 publications

Nafcillin-Induced Bullous Skin Eruption with Granulocytopenia in a Patient with End-Stage Renal Disease

Nafcillin-Induced Bullous Skin Eruption with Granulocytopenia in a Patient with End-Stage Renal Disease

Autoantitela k insulinu, sakharnyy diabet 1 tipa i diabeticheskaya nefropatiya

Skin manifestations of drug reactions

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