The new product development (NPD) activities of enterprises serve as a critical source of competitiveness. To effectively harness the opportunities presented by digital transformation and enhance the performance of NPD in organizations amidst the digital revolution is an area of concern that warrants attention. In this context, we conducted research using data from the annual reports of 35 listed mainboard enterprises in 2021. This research used the resource arrangement theory and the resource-structure-capability research framework. In addition, we utilized the quantitative comparative analysis (QCA) method to investigate how digital transformation capability, R&D investment capability, and heterogeneity synergies impact the performance of NPD. The findings indicate that: (1) Four distinct paths (i.e., digital innovation-driven, large-scale multi-talent, mature and robust, and digital start-up) drive improvements in NPD performance. Notably, there exists an asymmetric causal relationship between these four paths and the performance; (2) Digital transformation capability, firm R&D investment, and firm heterogeneity all contribute to enhancing NPD performance. However, they do not individually guarantee high performance. A synergistic effect of at least two factors is required to yield notable NPD performance; (3) Enterprise heterogeneity plays a pivotal role. Companies with different characteristics must opt for distinct digital transformation paths to improve their NPD performance; (4) In the initial stage of digital transformation, enterprises can enhance NPD performance by augmenting their investment in R&D personnel.