R. S. C.

Winter, Calvert J.; Castro, Raúl Silva

doi:10.2307/40075601

Cited by 7 publications

(2 citation statements)

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“…Multiple studies have been conducted evaluating the overall outcome after splenectomy. Unfortunately, these studies mainly entail information on survival times, oncological outcome, and intra operative complications, but do not report data on peri-or postoperative antibiotics [16][17][18][19][20][21][22][23][24][25][26][27][28]. None of these studies lists SSI as an adverse outcome.…”

Section: Discussionmentioning

confidence: 99%

Retrospective evaluation of surgical site infection after open splenectomies with and without perioperative prophylactic antibiotic coverage

Husi,

Arnaldi,

Roitner

et al. 2023

Tierarztl Prax Ausg K Kleintiere Heimtiere

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Objectives Perioperative prophylactic antibiotics (PPA) are widely used in veterinary medicine to prevent surgical site infections (SSI). Current guidelines advocate the use in clean procedures only if surgeries exceed 90 minutes, or in patients with an ASA score ≥3. Procedure specific recommendations are currently lacking. The following study aimed to analyze the protective effect of PPA in dogs undergoing open splenectomy. Methods The electronic database of our institution was searched for dogs that underwent splenectomy between 10/2017 and 01/2023. Data collection included age at presentation, breed, weight, reason for splenectomy, diagnosis, ASA class, PPA regime, surgery time, anesthesia time, lowest blood oxygen concentration during anesthesia, lowest body temperature, and lowest blood pressure during surgery as well as duration of hospitalization. Dogs were included if a follow-up of 30 days after surgery was available, or if death occurred within this timeframe. Results A total of 112 dogs were included. Of these, 46 dogs received PPA, and 66 did not. Most dogs were classified ASA 3 or higher (PPA 87%, non-PPA 80.3%). One SSI (1.5% SSI rate) occurred in the non-PPA group (overall SSI rate 0.9%). Due to the low SSI rate, statistical analysis of risk factors for SSI development was not possible. Conclusion The described infection rate of 1.5% without PPA indicates, that splenectomy does not qualify as high-risk surgery for SSI, even in patients with ASA class 3 or higher. Clinical Relevance As splenectomies are frequently performed, the findings of the current study could have a major impact on the overall antimicrobial burden in routine veterinary practice.

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Section: Discussionmentioning

confidence: 99%

Retrospective evaluation of surgical site infection after open splenectomies with and without perioperative prophylactic antibiotic coverage

Husi,

Arnaldi,

Roitner

et al. 2023

Tierarztl Prax Ausg K Kleintiere Heimtiere

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“…Besides, side-effects resulting from such therapy occur commonly after the patients have been discharged from hospital. These include rebound breast engorgement (Lubin, 1946;Gershenfeld and Perlmutter, 1948;Markin and Wolst, 1960;Winter and Robinson, 1964;Stirrat et al, 1968;Lee, 1971) and withdrawal bleeding (Arbabanel and Good- friend, 1940;Winter and Robinson, 1964;Lee, 1971).…”

mentioning

confidence: 99%

Inhibition of Postpartum Lactation With Single‐Dose Drugs

Lee

1972

Aust NZ J Obst Gynaeco

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A trial was undertaken with 2 single-dose drugs for the inhibition of postpartum lactation. Two hundred patients were studied, of whom one half were given a single oral tablet of quinestrol (Estrovis) 4 mg. and the other half were given a single intramuscular injection of Ablacton. The results showed that both preparations were equally effective in the initial inhibition of lactation and were rarely associated with rebound breast engorgement or withdrawal bleeding.

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