R-Substituent vs. exocyclic oxygen: influence on synthesis and crystal packing of R-[1,2,5]oxadiazolo[3,4-c]cinnoline mono- and dioxides

Abstract

A series of R-[1,2,5]oxadiazolo[3,4-c]cinnoline 5-mono- and 1,5-dioxides containing substituents (R = CH3, F, Br, CF3) at different positions were synthesized by an N-nitration-annulation process occurring upon treatment of 3-amino-4-(R-aryl)furazans and...