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Potassium carbonate as a green catalyst for Markovnikov addition of azoles to vinyl acetate in PEG

“…The residue was purified by silica gel column chromatography using ethylacetate: hexane (20:80) as an eluent. The structure of products was confirmed by IR, 1 HNMR, 13 CNMR, and HRMS/mass spectral data. All the products are known compounds.…”

“…J06.12 Hz) 13. C NMR (CDCl 3 , 75 MHz , d, ppm): 169.98, 136.91, 136.12, 114.01, 76.25, 21.35, 20.60, 14.21.…”

A Heteroleptic Bis(tridentate) Ruthenium(II) Platform Featuring an Anionic 1,2,3-Triazolate-Based Ligand for Application in the Dye-Sensitized Solar Cell

“…Note: Under the reaction conditions, a partial triazole N -alkylation, presumably due to the formation of a carbenium ion from the alcohol solvent under the acidic reaction conditions was observed; however, the minor side product was easily removed by trituration of the reaction mixture with MeOH/NEt 3 (9:1, v / v ). Nonetheless, TEGDME was chosen as solvent in case of 2b ( vide infra ) in order to circumvent this side reaction.…”

More Sustainable Approaches for the Synthesis of N-Based Heterocycles

“…Lin et al described a novel and highly efficient methodology for preparation of N-heterocycle derivatives with biological activity by Markovnikov’s addition using ionic liquids. The Markovnikov addition is a useful method to prepare C−C, C−N, and C−S compounds using in general harsh bases, strong acids, or high temperature, which would lead to undesirable byproducts and other residues. , The authors discovered that the use of ILs as a recyclable reaction media, as well as an efficient catalyst, for Markovnikov’s addition of N-heterocyclic compounds to vinyl esters affords the corresponding N-heterocycle derivatives in high yields under mild and neutral conditions ( Table ). The reactions performed in ILs containing BF 4 as anion exhibited excellent catalytic activity, while no reaction was observed in the case of ILs containing PF 6 as anion (entries 2 and 4).…”