Raccoon Eyes in Amyloidosis

Abstract

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Raccoon eyes as a diagnostic key for suspected amyloidosis

“…Raccoon eyes, characterized by ecchymotic lesions around the eyes, are a typical cutaneous manifestation. It is essential to differentiate this from other eyelid conditions, such as atopic eczema, ocular rosacea, contact dermatitis or DM [ 2 ]. Raccoon eyes in amyloidosis result from amyloid accumulation in periorbital blood vessels and dermal laxity, leading to vascular rupture, haemorrhage and amyloid deposits [ 1 , 2 ].…”

“…It is essential to differentiate this from other eyelid conditions, such as atopic eczema, ocular rosacea, contact dermatitis or DM [ 2 ]. Raccoon eyes in amyloidosis result from amyloid accumulation in periorbital blood vessels and dermal laxity, leading to vascular rupture, haemorrhage and amyloid deposits [ 1 , 2 ]. Recognizing raccoon eyes early is crucial for a timely diagnosis and better patient prognosis.…”