Race and Alopecia Areata amongst US Women

Thompson, Jordan M.; Park, Min Kyung; Qureshi, Abrar A.; Cho, Eunyoung

doi:10.1016/j.jisp.2017.10.007

Cited by 34 publications

(31 citation statements)

References 13 publications

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“…7,8,12 Similarly to prior studies, Caucasians were the predominant race both groups, 14 but African Americans were disproportionately affected by AA. 14,15 Our findings are consistent with previous research indicating atopic dermatitis as the most common comorbidity among paediatric AA patients, but our calculated prevalence (17.4%) is lower than previous estimates of 28.6-34.4%. 7,8 Previous estimates used information from a national registry, which may be subject to bias due to the voluntary nature of registration likely dependent on provider, patient and/or parent preferences.…”

Section: Discussionsupporting

confidence: 92%

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Comorbidities in pediatric alopecia areata

Conic

Tamashunas

Damiani

et al. 2020

Acad Dermatol Venereol

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Background Comorbidities are associated with higher health care costs, complex management, and poorer health outcomes. Identification and treatment of comorbid conditions in paediatric alopecia areata (AA) patients could provide an opportunity to improve health outcomes. Objectives To determine the prevalence of comorbidities among paediatric patients with AA using a large de-identified aggregated patient database. Methods This is a cross-sectional study using aggregated health record data through April 1, 2019. Patients ≤18 years of age, with alopecia areata (n = 3510) and without alopecia areata (n = 8 310 710) were identified. The primary outcome was the prevalence of comorbidities among AA patients. Results Of the 8 314 220 paediatric patients, 3510 (1570 males and 1940 females) had a diagnosis of alopecia areata. The most common comorbidities included atopic dermatitis (17.4% vs.

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Section: Discussionsupporting

confidence: 92%

“…Gender distribution is comparable to prior studies 7,8,12 . Similarly to prior studies, Caucasians were the predominant race both groups, 14 but African Americans were disproportionately affected by AA 14,15 …”

Section: Discussionsupporting

confidence: 74%

Comorbidities in pediatric alopecia areata

Conic

Tamashunas

Damiani

et al. 2020

Acad Dermatol Venereol

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“…Few studies have investigated these conditions among Native American populations. A recent study of examining racial disparities for alopecia areas using the Nurses' Health Study also reported higher percentages of individuals with the condition among African Americans and Other races (American Indian, Asian, Native Hawaiian, or Pacific Islander) [51]. Some evidence has been found for a higher rate of primary biliary cirrhosis among British Columbia's First Nation's population [52], and one study identified a substantive overlap between RA and Sjögren's syndrome for an Oklahoma Native American population [53,54].…”

Section: Discussionmentioning

confidence: 98%

Comparative United States autoimmune disease rates for 2010–2016 by sex, geographic region, and race

Roberts

Erdei

2020

Autoimmunity Reviews

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Purpose: AIDs may disproportionately impact specific racial groups, but autoimmune (AID) prevalence information by minority racial group is sparse for many AIDs. The objective of this analysis was to supplement previously published AID prevalence rates by providing information on race rate ratios (minority race populations compared to Caucasian populations) in the United States. Preliminary to estimating race rate ratios, contemporary US-specific, health care utilization-based AID prevalence rates and female-to-male ratios were estimated and compared to previously published AID prevalence rates. Methods:We used a large national electronic medical record database of 52 million individuals to estimate age-adjusted direct standardized rates for 22 AIDs for 2010 through 2016 by gender, race, and US census division. These were compared to previously published estimates.Results: Female-to-male ratios were comparable with published studies. Almost all observed Multiracial AID rates were significantly higher than Caucasian rates, as well as 9 of 22 AID rates observed among Native Americans and 8 of 22 AID rates estimated among African-American patients. Regional variation was noted: highest African-American systemic lupus erythematosus rates were observed in the West North Central and South Atlantic divisions, highest African-American multiple sclerosis rates in the South Atlantic and Pacific divisions, and highest Native American rheumatoid arthritis rates in the West North Central, Mountain, and Pacific divisions.Conclusions: Substantial AID heterogeneity exists by race and by geographic area. An important research area is further exploring factors related to heterogeneity such as potential interactions between genetic susceptibility and environmental factors.

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“…Alopecia areata (AA) is a T-cell mediated, autoimmune disorder which is mainly affecting anagen hair follicles and nails. Clinically, AA usually presents with localized circumscribed patches of nonscarring hair loss [1]. Alopecia totalis (AT) is a subtype of AA which is characterized by total hair loss on the face and scalp, whereas alopecia universalis (AU) is the other subtype of AA manifesting with generalized hair loss on hair-bearing regions of the body.…”

Section: Introductionmentioning

confidence: 99%

Demographic and Clinical Features of 1,641 Patients with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis: A Single-Center Retrospective Study

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Engın

Serdaroğlu

et al. 2020

Skin Appendage Disord

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Background/Aim: Alopecia areata (AA) is a common autoimmune hair disorder which is characterized by noncicatricial hair loss. AA commonly presents with localized patches on the scalp and face but may affect any hair-bearing region of the body leading to even more generalized involvement. AA may affect any age group, gender, and race. The current study investigates the demographic characteristics of the patients with AA and subgroups of AA including alopecia totalis (AT) and alopecia universalis (AU) and the prevalence of disease, sex, and age distribution and seasonal variation retrospectively in a tertiary dermatology clinic in Turkey. Materials and Methods: In this retrospective, cross-sectional study, 1,641 patients diagnosed with AA, AT, and AU in the dermatology clinic of a public university hospital were included. The dermatology outpatient database was reviewed retrospectively. The diagnosis of AA was based on patient history, clinical examinations, and histopathologic findings. Results: Fifty-four thousand one hundred sixty-eight patients were admitted to our outpatient clinic in 4 years time, and 1,641 were diagnosed as having AA, AT, and AU. One thousand three hundred ninety-two patients (84.8%) had AA, 81 (4.9%) had AT, and 168 (10.2%) had AU. Among the 1,641 patients included in the study, 877 were females (53.4%) and 764 were males (46.6%). The mean age was 29.86 ± 14.48 years in AA, 29.50 ± 16.18 in AT, and 32.81 ± 14.48 in AU; 77.4, 72.8, and 68.5% of patients were aged under 40 years in AA, AT, and AU. There was no statistically significant difference in seasonal presentation times. Conclusion: AA is affecting approximately 2% of the general population without any sex, race, or age group predilection. In this study, we found a lower prevalence of AA in the pediatric age group in comparison with adults. This finding may support the hypothesis of the increasing prevalence of AA over time. The higher ratio of AA regarding this study may support that the frequency of AA and subtypes varies between regions.

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Race and Alopecia Areata amongst US Women

Cited by 34 publications

References 13 publications

Comorbidities in pediatric alopecia areata

Comorbidities in pediatric alopecia areata

Comparative United States autoimmune disease rates for 2010–2016 by sex, geographic region, and race

Demographic and Clinical Features of 1,641 Patients with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis: A Single-Center Retrospective Study

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