Racial residential segregation is associated with health inequalities in the USA, and one of the primary mechanisms is through influencing features of the neighborhood physical environment. To better understand how Black residential segregation might contribute to health risk, we examined retail redlining; the inequitable distribution of retail resources across racially distinct areas. A combination of visual and analytic methods was used to investigate whether predominantly Black census block groups in New York City had poor access to retail stores important for health. After controlling for retail demand, median household income, population density, and subway ridership, percent Black was associated with longer travel distances to various retail industries. Our findings suggest that Black neighborhoods in New York City face retail redlining. Future research is needed to determine how retail redlining may perpetuate health disparities and socioeconomic disadvantage. Racial residential segregation is thought to be the foundation on which Black-White disparities in health status have been built. 42 Three primary mechanisms through which segregation operates include: (1) the concentration of poverty, (2) constrained access to economic and educational opportunity structures, and (3) neighborhood social and physical environments, including housing quality and the distribution of amenities and retail resources. 16,24,34,35,41,42 These pathways create economic, social, and physical contexts that determine the likelihood of conditions that foster, support, or sustain health.One of the primary constituents of a healthy neighborhood is the provision of public or private services that support people in their daily lives. 21 Public or private services include education, transportation, health care, and retail services. These services, along with the reputation of an area, are important neighborhood features. Reputation influences how areas are perceived by residents, service planners and investors, and in turn, availability of services. 21 Black segregated neighborhoods Kwate and Saldana are with the