Racialised people in clinical guideline panels

Persaud, Nav; Ally, Muhamad Z; Woods, Hannah; Workentin, Aine; Baxter, Nancy N.; Boozary, Andrew; Grundy, Quinn; Lofters, Aisha; McKenzie, Kwame; Pinto, Andrew D.; Straus, Sharon E.

doi:10.1016/s0140-6736(21)02759-8

Cited by 23 publications

(23 citation statements)

References 7 publications

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“…Antimicrobial resistance (AMR) is a global problem, but this systematic analysis of the burden in 204 countries is the most comprehensive yet in estimating the distribution of and the leading pathogen-drug combinations causing AMR. 1 The authors found that 4.95 million deaths (95% confidence interval (CI) 3.62-6.57) were associated with AMR in 2019, of which they determined 1.27 million deaths (95% CI 0.91-1.71) were caused by AMR. The death rate was highest in western Sub-Saharan Africa at 27.3 deaths per 100 000 (20.9-35.3) and lowest in Australasia at 6.5 deaths (4.3-9.4) per 100 000 (Fig.…”

Section: Global Burden Of Antimicrobial Resistancementioning

confidence: 99%

Global burden of antimicrobial resistance

2022

J Paediatrics Child Health

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a median of 14 members (interquartile range 10-19), which included a median of 5 (3-8) women, 9 (5-11) men, 2 (1-4) non-white and 11 (7-14) white members. The selection process for panels was often unstated or unclear. Most guideline publications (55%) did not mention gender or race in the recommendations or supporting text. We should be vigilant for structural racism 2 and gender disparities, which are pervasive within academic medicine and throughout society.

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Section: Global Burden Of Antimicrobial Resistancementioning

confidence: 99%

Global burden of antimicrobial resistance

2022

J Paediatrics Child Health

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“…How many of us sitting on a panel writing clinical practice guidelines have paused to consider the composition of the panel, the balance of women and men, non‐white and white? Canadian researchers 1 argue that ‘guideline panels should comprise individuals positioned to make relevant recommendations, including those that reflect the diversity of the priority population’. They analysed all 237 clinical practice guidelines published in national general medical journals from Australia, Canada, the UK and the USA between June 2014 and June 2021.…”

Section: Figmentioning

confidence: 99%

“…European researchers randomised 74 children aged 1-7 years, mean 5.6 (standard deviation = 1.6) years, to receive insulin via either a closed-loop system or sensoraugmented pump therapy (control) for 16 weeks; they then crossed over to the other treatment for 16 weeks in a multicentre, randomised, cross-over trial. 1 The closed-loop period was significantly superior to standard pump therapy in terms of time with glucose levels in the target range (72 vs. 63%, P < 0.001, which equated to a clinically significant 125 min/day), time spent in a hyperglycaemic state, difference in glycated haemoglobin level and difference in mean sensor glucose level (Fig. 1).…”

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confidence: 94%

Composition of panels writing clinical practice guidelines

2022

J Paediatrics Child Health

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“…Despite initiatives to advance the inclusion of women and members of historically marginalized groups in academic medicine and biomedical research, gender and racial inequities remain 1. Inequities are recognized in compensation, senior leadership positions, highly cited research publications, and professional society awards 234.…”

Section: Introductionmentioning

confidence: 99%

Women and non-white people among Lasker Award recipients from 1946 to 2022: cross sectional study

Jacobs

Bibb

Allen

et al. 2023

BMJ

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Objective To determine whether gender and racial inequities exist among Lasker Award recipients. Design Observational, cross sectional analysis. Setting Population based study. Participants Recipients of four Lasker Awards from 1946 to 2022. Main outcome measures Gender and race (non-white categorized as racialized v white categorized as non-racialized) of all Lasker Award recipients. Personal characteristics of award recipients were categorized by four independent authors using previously established methods and consistency of categorization among authors was analyzed. Women and non-white people were thought to be underrepresented among Lasker Award recipients compared with professional degree recipients overall. Results Among 397 Lasker Award recipients since 1946, 92.2% (366/397) were men. Most award recipients were identified as white (95.7%, 380/397). One non-white woman was identified as having received a Lasker Award over the course of seven decades. The proportion of women among award recipients in the most recent decade (2013-22) is similar to the first decade of awards (1946-55; 15.6%, 7/45 v 12.9%, 8/62). The median timeframe from terminal degree receipt to Lasker Award conferral for all award recipients is 30 years. The proportion of women who received a Lasker Award between 2019 and 2022 (7.1%) was less than would be expected based on the proportion of life science doctorates awarded to women in 1989 (30 years previously; 38.1%). Conclusions The number of women and non-white people in academic medicine and biomedical research continues to increase, yet the proportion of women among Lasker Award recipients has not changed in more than 70 years. Additionally, time from terminal degree receipt to Lasker Award conferral does not appear to fully account for the observed inequities. These findings establish the need for further investigation of possible factors that could hinder women and non-white people from entering the pool of eligible award recipients, potentially limiting the diversification of the science and academic biomedical workforce.

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Racialised people in clinical guideline panels

Cited by 23 publications

References 7 publications

Global burden of antimicrobial resistance

Global burden of antimicrobial resistance

Composition of panels writing clinical practice guidelines

Women and non-white people among Lasker Award recipients from 1946 to 2022: cross sectional study

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