Radial Endobronchial Ultrasound (EBUS) Guided Suction Catheter-Biopsy in Histological Diagnosis of Peripheral Pulmonary Lesions

Zarić, Bojan; Stojšić, Vladimir; Carapic, Vladimir; Kovačević, Tomi; Stojanović, Goran; Panjković, Milana; Kioumis, Ioannis; Darwiche, Kaid; Zarogoulidis, Konstantinos; Stratakos, Grigoris; Tsavlis, Drosos; Hohenforst-Schmidt, Wolfgang; Pitsiou, Georgia; Zissimopoulos, Athanasios; Sachpekidis, Nikos; Karapantzos, Ιlias; Karapantzou, Chrysanthi; Zarogoulidis, Paul; Perin, Branislav

doi:10.7150/jca.13081

Cited by 47 publications

(41 citation statements)

References 23 publications

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“…In previous years, the most common diagnostic tools for lung cancer included CT, X-chip imaging, and sputum cytology examination. However, these methods lack sensitivity and specificity, and often lead to misdiagnosis (Sasaki et al, 2016;Zaric et al, 2016). Currently, medical imaging, bronchoscopy, bronchial perfusion fluid examinations, and tissue pathology analyses are widely used in lung cancer screening and early diagnosis (Huang et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

Combination of IL-6, IL-10, and MCP-1 with traditional serum tumor markers in lung cancer diagnosis and prognosis

Pan¹,

Zhou²,

Wang³

et al. 2016

Genet. Mol. Res.

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Section: Discussionmentioning

confidence: 99%

Combination of IL-6, IL-10, and MCP-1 with traditional serum tumor markers in lung cancer diagnosis and prognosis

Pan¹,

Zhou²,

Wang³

et al. 2016

Genet. Mol. Res.

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“…International Publisher electromagnetic navigation and cone beam ct bronchoscopy [1][2][3]. At advance stage disease we need tissue biopsies for non-small lung cancer patients in order to investigate the expression of a number of genes which are associated with the treatment options of a patient [4][5][6].…”

Section: Ivyspringmentioning

confidence: 99%

Sex Differences and Adverse Effects between Chemotherapy and Immunotherapy for Non-Small Cell Lung Cancer

et al. 2020

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Introduction: Lung cancer remains the leading cause of cancer mortality in men and women and around the world. Approximately 90% of cases of lung cancer are caused by smoking and the use of tobacco products. However, other factors such as asbestos, air pollution and chronic infections can contribute to pulmonary carcinogenesis. Lung cancer is divided into two broad histological categories, which develop and spread different small cell lung carcinomas and non-small cell lung carcinomas. The treatment options for lung cancer include surgery, radiotherapy, chemotherapy and targeted treatments. Tumor induced immune suppression is vital for malignant progression. Immunotherapies act by strengthening the patient's innate tendency for an immune response and give positive promise to patients with non-small cell lung cancer and small cell lung cancer. Immune checkpoint inhibitors are a new approach to cancer therapies. Just as immune therapies include a new approach to cancer biology, the toxicities associated with these factors have created new challenges in clinical practice. Materials & Methods: Patients (218) aged 40-80 years were treated with either chemotherapy or immunotherapy. Their response to treatment and any subsequent adverse drug reactions were studied. Results: 69% of patients were treated with chemotherapy and 31% were treated with immunotherapy. The type of treatment had a statistically significant effect on the undesirable effects of the treatment. Conclusions: The type of treatment was statistically significant in responding to the treatment and treatment side effects but not in the rate of death.

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“…Both these techniques have also shown by various workers to improve yield. [13262728] However, this technology has yet to be introduced in India.…”

Section: Discussionmentioning

confidence: 99%

Radial endobronchial ultrasound for the diagnosis of bronchoscopically invisible lesions: First case series from India

et al. 2017

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Background:A peripheral, bronchoscopically invisible pulmonary lesion is a diagnostic challenge. Transthoracic needle aspiration has long been the investigation of choice but runs the risk of pneumothorax (up to 44%). Newer technologies like radial endobronchial ultrasound (R-EBUS) offer a safer approach. We present our results of R-EBUS in the diagnosis of bronchoscopically invisible lesions. This is the first large case series from India.Aims:(1) To determine the yield of R-EBUS for the diagnosis of bronchoscopically invisible lesions. (2) To compare the yields of forceps versus cryobiopsies in the diagnosis of these lesions.Setting:Tertiary care cancer center.Design:Prospective study.Methods:Consecutive patients presenting between January and October 2015 with bronchoscopically invisible peripheral pulmonary lesions were included. R-EBUS was used to localize and sample the lesion and the yields were analyzed. Yields of cryo and forceps biopsy were compared where both methods had been used. Data were analyzed using SPSS version 22.Results:A definite diagnosis obtained in 67.3% (37/55) patients with no major complications. No significant difference was found in yield between: (1) small (<3 cm) and large (>3 cm) lesions: (46.2% versus 78.6%, P = 0.38). (2) central and adjacent lesions: 61.5% versus 70%. (3) forceps and cryobiopsy (n = 28, 75% versus 67.9% P = 0.562).Conclusions:R-EBUS is a safe procedure in our setting and its yield is comparable to that reported in literature. The yield of central and adjacent lesions and forceps or cryobiopsy appears similar. Further refinements in the technique could improve yield.

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Radial Endobronchial Ultrasound (EBUS) Guided Suction Catheter-Biopsy in Histological Diagnosis of Peripheral Pulmonary Lesions

Cited by 47 publications

References 23 publications

Combination of IL-6, IL-10, and MCP-1 with traditional serum tumor markers in lung cancer diagnosis and prognosis

Combination of IL-6, IL-10, and MCP-1 with traditional serum tumor markers in lung cancer diagnosis and prognosis

Sex Differences and Adverse Effects between Chemotherapy and Immunotherapy for Non-Small Cell Lung Cancer

Radial endobronchial ultrasound for the diagnosis of bronchoscopically invisible lesions: First case series from India

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