The nonlinear, steady, and mixed convective boundary layer flow and heat transfer of an incompressible tangent hyperbolic non‐Newtonian fluid over an isothermal wedge in the presence of magnetic field are analyzed numerically using the implicit Keller‐Box finite‐difference technique. The entropy analysis due to MHD flow of a tangent hyperbolic fluid past an isothermal wedge and viscous dissipation is also included. The numerical code is validated with previous Newtonian studies available in the literature. Graphical and tabulated results are analyzed to study the behavior of the fluid velocity, temperature, concentration, shear stress, heat transfer rate, entropy generation number, and Bejan number for various emerging thermophysical parameters, namely Weissenberg number (We), power‐law index (n), mixed convection parameter (λ), pressure gradient parameter (m), Prandtl number (Pr), Biot number (γ), Hartmann number (Ha), Brinkmann number (Br), Reynolds number (Re), and temperature gradient (Π). It is observed that velocity, entropy, Bejan number, and surface heat transfer rate are reduced with the increase in the Weissenberg number, but temperature and local skin friction are increased. An increase in pressure gradient enhances velocity, entropy, local skin friction, and surface heat transfer rate, but reduces temperature and Bejan number. An increase in an isothermal power‐law index (n) is observed to increase velocity, Bejan number, and surface heat transfer rate, but it decreases temperature, entropy, and local skin friction. An increase in the magnetic parameter (Ha) is found to decrease temperature, entropy, surface heat transfer rate, and local skin friction, and it increases velocity and Bejan number. The research is applicable for coating materials in chemical engineering, for instance, robust paints, production of aerosol deposition, and water‐soluble solution thermal treatment.