The paper carries out an analysis on the momentum, heat and mass transfer characteristics in an incompressible magnetohydrodynamic non-Newtonian boundary flow of a viscoelastic fluid over a stretching sheet in the presence of thermal diffusion and chemical reaction. The partial differential equations governing the flow as well as heat and mass transfer features are converted into highly non-linear coupled ordinary differential equations by similarity transformations. The resulting differential equations are solved by using a shooting technique with fifth-order Runge-Kutta-Fehlberg integration scheme. The influence of magnetic interaction, variable thermal conductivity, viscoelastic, variable fluid viscosity, heat source/sink rate of chemical reaction, themal radiation and thermal diffusion parameters as well as Prandtl and Schmidt numbers are analyzed for velocity, temperature and concentration profiles. The wall shear stress, wall temperature and concentration gradients are also investigated for the problem. The fluid viscosity varies as an inverse function of velocity while the thermal conductivity assumes a linear and an inverse function of temperature and concentration respectively. The study shows that the thermal diffusion and thermal radiation parameters have opposite effects on the skin friction coefficient and wall concentration gradient. However, the rate of chemical reaction has similar influence on the skin friction coefficient and wall temperature gradient.