Radiation as the Sole Mode of Treatment in Carcinoma of the Breast

Amalric, R; Spitalier, J. M.

doi:10.1007/978-3-642-95377-4_6

Cited by 4 publications

(1 citation statement)

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“…Actuellement nous disposons de 1440 cas ayant un recul de plus de 5 ans et de 320 cas ayant un recul de plus de 10 ans; le tiers de ces patientes a été irradié après tumorectomie pre mière. [2,3] Le but des irradiations après chirurgie conservatrice limitée est de donner non seule ment une dose cytostatique au niveau du lit tumoral et de l'aisselle (si elle est histologique ment envahie) mais aussi de distribuer d'une manière homogène une dose suffisante à l'ensemble de la glande mammaire et des aires ganglionnaires tributaires pour retirer la fertilité d'éventuels foyers néoplasiques infracliniques, microscopiques. …”

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La radiothérapie des cancers du sein après tumorectomie et leur surveillance

Amalric¹,

Robert²,

Altschuler³

et al. 1981

Gynäkol Geburtshilfliche Rundsch

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A chronological homogeneous series of 467 breast cancers has been treated from 1969 to 1974 by tumorectomy followed by irradiation at curative doses: 75 Gy over a period of 7.5 weeks (60 Gy by telecesium and 25 Gy by accelerated electrons). The tumors were exclusively T1 T2/N0 and N1 according to the UICC classification. Symptom-free survival for more than 5 years was achieved in 80% of the cases. Survival was of 88% in the case of T1/N0 tumors and conservation of the breast with a good esthetic result was obtained in 90% (only 2 % invalidating sequelae from radiotherapy). These results could be maintained at 10 years with a survival rate of 77%. In order to achieve maximum security in the supervision of irradiated breast cancers, clinical tests, infrared thermography and radiology should be systematically used. Each method makes approximately 10% of errors, either by excess of by default; combination of these three methods reduces these errors by 4 in either way. One can thus intervene in time in the case of nonsterilized tumors (at about the 10th month) or in the case of a recurrence (at about the 30th month); 60% survival of more than 5 years will then be obtained by surgery.

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