Radiation dose considerations by intra-individual Monte Carlo simulations in dual source spiral coronary computed tomography angiography with electrocardiogram-triggered tube current modulation and adaptive pitch

May, Matthias; Deak, Paul; Kuettner, Axel; Lell, Michael; Wuest, Wolfgang; Scharf, Michael; Keller, Andrea; Häberle, Lothar; Achenbach, Stephan; Seltmann, Martin; Uder, Michael; Kalender, Willi A.

doi:10.1007/s00330-011-2300-6

Cited by 7 publications

(3 citation statements)

References 40 publications

(52 reference statements)

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“…Recently, some scanners have been used for CTCA by using the tube current modulation (TCM) technique. May et al [21] reported that radiation dose savings up to 52% were If images having good noise properties are needed, choosing a smooth reconstruction kernel is the most effective rather than increasing the tube current or selecting other acquisition modes. It is also effective to apply an iterative reconstruction algorithm.…”

Section: Discussionmentioning

confidence: 99%

Radiation doses, noise properties, and in-plane spatial resolutions for CT coronary angiography using different CT scanners: Phantom study

Matsubara

Takata

Mori

et al. 2015

IJDI

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Objective: We aimed to evaluate radiation doses, noise properties, and in-plane spatial resolutions for CT coronary angiography (CTCA) using different CT scanners and phantoms.Methods: ECG-gated step-and-shoot (SAS) and low-pitch spiral (LPS) acquisitions were performed using the 64-section single-source CT (SSCT) system. ECG-gated high-pitch spiral (HPS), SAS, and LPS acquisitions were performed using the 128-section dual-source CT (DSCT) system. The absorbed doses for thoracic organs were measured using an anthropomorphic phantom and radiophotoluminescent glass dosimeters. Noise properties and in-plane spatial resolutions were evaluated using a calibration phantom and a cylinder phantom constructed in-house, respectively. Results:The absorbed doses for thoracic organs differed significantly depending on the acquisition modes and not the scanners. The doses absorbed by the heart were 66.8 and 215.5 mGy with SAS and LPS acquisitions using the 64-section SSCT system, respectively, and 10.0, 96.1, and 195.7 mGy with HPS, SAS, and LPS acquisitions using the 128-section DSCT system, respectively. Noise properties and in-plane spatial resolutions differed significantly depending on the scanners used but not the acquisition modes. Conclusions:To optimize the patient dose, an appropriate acquisition mode should be chosen according to the scanner type, patient's average heart rate, stability of a patient's heartbeat, and patient's history.

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Section: Discussionmentioning

confidence: 99%

Radiation doses, noise properties, and in-plane spatial resolutions for CT coronary angiography using different CT scanners: Phantom study

Matsubara

Takata

Mori

et al. 2015

IJDI

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“…Examples of optimisation of a diagnostic procedure based on patient characteristics are contrast media dosing based upon patient weight [ 9 , 10 ], scan delay in MR or CT angiography based on bolus tracking. Examples of patient characteristics used to reduce side effects of the diagnostic procedure are measures to avoid the use of ionising radiation when imaging children and pregnant women [ 11 , 12 ], to prevent the use of IV contrast media in patients with eGFR < 30 ml/min/1.73 m² [ 13 ], and automated tube voltage selection and tube current modulation in CT based on measured attenuation [ 14 , 15 ].…”

Section: Personalised Diagnostic Proceduresmentioning

confidence: 99%

Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR)

2015

Insights Imaging

123

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“…Thus, MP-CTA may be preferred for much greater diagnostic value than SP-CTA. However, even with ECG tube current modulation (TCM), the average effective dose of a MP-CTA scan could be much higher than 10 mSv ( May et al 2012 )_ENREF_50 (6 ~ 24 at Mayo Clinic), depending on the width of the pulse window and patient size ( Weustink et al 2008 )_ENREF_51. Taking 80% patients with negative findings into account, minimizing the radiation dose becomes a major and urgent need for a broader application of MP-CTA for CAD diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Spatiotemporal denoising of low-dose cardiac CT image sequences using RecycleGAN

Zhou,

Yang,

Konduri

et al. 2023

Biomed. Phys. Eng. Express

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Electrocardiogram (ECG)-gated multi-phase computed tomography angiography (MP-CTA) is fre-quently used for diagnosis of coronary artery disease. Radiation dose may become a potential concern as the scan needs to cover a wide range of cardiac phases during a heart cycle. A common method to reduce radiation is to limit the full dose acquisition to a predefined range of phases while reducing the radiation dose for the rest. Our goal in this study is to develop a spatiotemporal deep learning method to enhance the quality of low-dose CTA images at phases acquired at reduced radiation dose. Recently, we demonstrated that a deep learning method, Cycle-Consistent generative adversarial networks (CycleGAN), could effectively denoise low-dose CT images through spatial image translation without la-beled image pairs in both low-dose and full-dose image domains. As CycleGAN does not utilize the temporal information in its denoising mechanism, we propose to use RecycleGAN, which could trans-late a series of images ordered in time from the low-dose domain to the full-dose domain through an additional recurrent network. To evaluate RecycleGAN, we use the XCAT phantom program, a highly realistic simulation tool based on real patient data, to generate MP-CTA image sequences for 18 patients (14 for training, 2 for validation and 2 for test). Our simulation results show that RecycleGAN can achieve better denoising performance than CycleGAN based on both visual inspection and quantitative metrics. We further demonstrate the superior denoising performance of RecycleGAN using clinical MP-CTA images from 50 patients.

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Radiation dose considerations by intra-individual Monte Carlo simulations in dual source spiral coronary computed tomography angiography with electrocardiogram-triggered tube current modulation and adaptive pitch

Cited by 7 publications

References 40 publications

Radiation doses, noise properties, and in-plane spatial resolutions for CT coronary angiography using different CT scanners: Phantom study

Radiation doses, noise properties, and in-plane spatial resolutions for CT coronary angiography using different CT scanners: Phantom study

Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR)

Spatiotemporal denoising of low-dose cardiac CT image sequences using RecycleGAN

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