Radiation dose rates of differentiated thyroid cancer patients after 131I therapy

Abstract

Postoperative I treatment for differentiated thyroid cancer (DTC) can create a radiation hazard for nearby persons. The present prospective study aimed to investigate radiation dose rates inI-treated DTC patients to provide references for radiation protection. A total of 141 I-treated DTC patients were enrolled, and grouped into a singular treatment (ST) group and a repeated treatment (RT) group. The radiation dose rate of I-treated patients was measured. The rate of achieving discharge compliance and restricted contact time were analyzed based on Chinese regulations. Multivariate logistic regression analysis was used to analyze the independent factors associated with the clearance of radioiodine. The rate of achieving discharge compliance (I retention < 400 MBq) was 79.8 and 93.7% at day 2 (D2) for the ST and RT groups, respectively, and reached 100% at D7 and D4, respectively. The restricted contact time with I-treated patients at 0.5 m for medical staff, caregivers, family members, and the general public ranged from 4 to 7 days. Multivariate logistic regression analysis showed that the 24-h iodine uptake rate was the only significant factor associated with radioiodine clearance. For the radiation safety ofI-treated DTC patients, the present results can provide radiometric data for radiation protection.

Effectiveness of mobile robots collecting vital signs and radiation dose rate for patients receiving Iodine-131 radiotherapy: A randomized clinical trial

“…Patients receiving 131I treatment after thyroidectomy exposes to the corresponding radiation to others, due to the accumulation of radionuclides in the body. During the period of taking radioactive drugs, patients are equivalent to a mobile radioactive source, which causes certain radiation damage to medical staff, family members, and other patients, making it necessary to take isolation and protective measures ( 13 , 14 ). With the environment of the radioactive ward around, there was much inconvenience for medical staff to collect vital signs and radiation doses of patients with radioactive sources.…”

Avaliação das glândulas salivares por exame de ultrassonografia cervical em pacientes antes e após tratamento de radioiodoterapia no câncer diferenciado da tireoide

“…De acordo com as diretrizes da ATA (2016), a RIT é indicada para pacientes com diagnóstico de CDT, exceto aqueles de baixo risco, com tamanho de tumor <1cm, sem extensão extra tireoidiana e sem metástases à distância ou linfonodos (8)(9)(10). A eficiência desse tratamento depende de fatores como a atividade de 131I absorvida pelas células tireoidianas remanescentes ou pelo tumor, preparação adequada do paciente e características tumorais específicas como histologia e estadiamento do tumor (7,8,11).…”