2010
DOI: 10.1016/j.ijrobp.2009.05.071
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Radiation Dose–Volume Effects in the Stomach and Small Bowel

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Cited by 474 publications
(356 citation statements)
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“…grade 2, the V45Gy for bowel cavity should be limited to 195 cm 3 [23]. While this constraint is satisfied for all patients planned with the CT-based strategy, it is not achieved in any of the patients planned with the CBCT-based strategy.…”
Section: Discussionmentioning
confidence: 99%
“…grade 2, the V45Gy for bowel cavity should be limited to 195 cm 3 [23]. While this constraint is satisfied for all patients planned with the CT-based strategy, it is not achieved in any of the patients planned with the CBCT-based strategy.…”
Section: Discussionmentioning
confidence: 99%
“…For the stomach and duodenum, the maximum dose was limited to 45 Gy, and the volume receiving > 22.5 Gy was limited to < 5 cm 3 (Table 2). 22 It was also required that prescription dose cover at least 95% of the PTV and 100% of the GTV when D mean was kept below 28 Gy. RT for HCC was delivered with linear accelerators (Varian Trilogy ™ ) using either 6 MV or 15 MV X‐rays.…”
Section: Methodsmentioning
confidence: 99%
“…However, the knowledge of dose-response and volume effects for normal tissue toxicity after CRT and surgery for rectal cancer is extremely limited. Some publications have studied acute toxicity, especially for bowel (62) and bladder (63), but dose plan factors affecting late toxicity are not well understood, especially not for conformal treatments (64,65). Some discrepancies in toxicity outcomes in the previously described studies could potentially be explained by variations in the plan optimization metrics used some studies might have been conducted using treatments planned with suboptimal dose constraints.…”
Section: Technological Advances and Organ-preservation Strategiesmentioning
confidence: 99%