Radiation Doses from Small-Bowel Follow-Through and Abdominopelvic MDCT in Crohn's Disease

Jaffe, Tracy A.; Gaca, A; Delaney, Susan; Yoshizumi, Terry T.; Toncheva, Greta; Nguyen, Giao; Frush, Donald P.

doi:10.2214/ajr.07.2427

Cited by 175 publications

(108 citation statements)

References 58 publications

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“…First, both scanning methods require the intake of a contrast agent or colonic luminal distension or bowel cleansing, which requires long preparation and discomfort. Second, with regard to CT, patients are exposed to a large dose of radiation, and it is a difficult issue because IBD patients often require frequent re-evaluations of the disease status [10,11]. Finally, MRI, despite being radiation-free, remains time consuming, expensive, and is not widely available in all centers.…”

Section: Introductionmentioning

confidence: 99%

SICUS and CEUS imaging in Crohn’s disease: an update

et al. 2017

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Endoscopy remains the main technique in the diagnosis and treatment of Crohn's disease (CD); nevertheless, the recent development of innovative and non-invasive imaging techniques has led to a new tool in the exploration of small bowel in CD patients. This paper reviews the available data on ultrasound imaging used for the evaluation of CD, highlighting the role of small intestine contrast-enhanced ultrasonography with the use of oral and intravenous contrast agents.Keywords Crohn's disease Á Contrast-enhanced ultrasound Á Small intestine contrast ultrasonography Sommario Nell'iter diagnostico e terapeutico della malattia di Crohn l'endoscopia rappresenta la principale metodica strumentale. Tuttavia, la recente introduzione di tecniche di imaging innovative e non invasive ha implementato lo studio dell'intestino nelle malattie infiammatorie croniche intestinali. La seguente revisione raccoglie i dati disponibili in letteratura relativi all'utilizzo dell'ecografia con mezzo di contrasto, sia orale (SICUS) sia endovenoso (CEUS), nella valutazione dei pazienti affetti da malattia di Crohn.

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Section: Introductionmentioning

confidence: 99%

SICUS and CEUS imaging in Crohn’s disease: an update

et al. 2017

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“…In order to evaluate the dose of a patient by direct method, dose measuring on patient or humanoid phantom by using an ionization chamber or small size devices such as TLDs and OSLs etc. [20]- [27]. The another way to assess organ doses as mentioned above is indirect method through measurement of CT dose indexes (CTDI) and published conventional factors obtained from Monte Carlo simulation and mathematical phantoms [21] [28]- [33].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Organ Dose by Direct and Indirect Measurements for a Wide Bore X-Ray Computed Tomography Unit That Used in Radiotherapy

Cakmak¹,

Tunçel²,

Sindir³

2015

IJMPCERO

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The aim of this study was to investigate the organ doses of patients undergoing computed tomography (CT) examination using the wide bore General Electric (GE) "Light Speed RT" unit. The head, chest and pelvic regions of the Rando-phantom were scanned with 120 kV, 200 mA, and 2.5 mm slice thickness for helical and axial modes. Thermoluminescent Dosimeter (TLD) pairs were used for the dosimetry of 10 organs. TL-counts were converted to dose by using CTDIcenter dose on CT-phantom. For the calculation of the organ doses, the ImPACT software was utilized by entering CTDIair (100 mAs) in small and large field of view (26.43 and 21.17 mGy respectively). The in-field dose ranges in helical and axial modes were 64.3 -38 mGy and 47.6 -19.7 mGy in head, 48.3 -14.1 mGy and 34.1 -10 mGy in chest, 28.4 -10.2 mGy and 21 -8.5 mGy in pelvic, respectively. The organ doses from software and TLD were compared and tailored as the in-field and the out-field radiation. First results showed that the organ dose was relatively higher in the helical mode on both direct and indirect measurement. The in-field organ dose differences between TLD and software were seen. In helical and axial modes, the dose differences ranged from +1 to +13.3 and −8.3 to +9.6 mGy for head exam, +1.1 to +15.3 and +0.3 to +9.1 mGy for chest, and −21.7 to +1.9 and −15.5 to +1.8 mGy for pelvic. The availability of this program for organ dose calculations by measuring CTDIair value for CT device used in the radiotherapy would be considered valuable.

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“…BT'de effektif doz ortalama 16,1 mSv dir. 10 mSv üzeri effektif dozda ölümcül kanser riski 1/2000 dir [10][11][12].…”

Section: Discussionunclassified

Diagnostic value of MR enterography for the assessment of small-bowel diseases

Allahverdiyev¹,

Koplay²,

Erdoğan³

et al. 2017

Archives of Clinical and Experimental Medicine

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ÖzAmaç: Bu çalışmamızda kolay elde edilebilen ve iyi bir bağırsak distansiyonu sağlayan %3 mannitol ile manyetik rezonans (MR) enterografi yönteminin tanısal etkinliğinin değerlendirilmesini amaçlıyoruz. Yöntemler: Yaşları 7-71 yıl arasında değişen 42 hasta çalışmaya dahil edildi. MR enterografi protokolü 1.5 Tesla MRG (Magnetom Aera; SiemensMedical Solutions, Erlangen, Germany) cihazı ile yapıldı. Bulgular cerrahi-fiberoptik kolonoskopiden elde edilen histopatolojik sonuçlarla karşılaştırıldı. Duyarlılık, özgüllük, pozitif ve negatif öngörü değerleri, tanısal doğruluk oranı istatiksel olarak hesaplandı. Bulgular: Duyarlılık %83, özgüllük %93, pozitif öngörü değeri %83, negatif öngörü değeri %93 ve tanısal doğruluk oranı %90 olarak saptanmıştır. Yalancı negatif olan iki hasta radyolojik olarak normal değerlendirildi, ancak patolojik inceleme nonspesifik inflamasyon olarak geldi. Yalancı pozitif olan bir hastada patolojik inceleme ülseratif kolit olarak, bir hastada ise invajinasyona neden olan ektopik pankreas dokusuna ait polipoid kitle saptandı. Gerçek pozitif olan dokuz hastada patoloji sonucu Crohn hastalığı, diğer hastada ise tipik olmamakla birlikte Crohn hastalığı lehine değerlendirildi. Ayrıca Crohn hastalığ ile takip edilen bir hastada iki yerde ince bağırsak segment tutulumu, diğer bir hastada da ileoileal fistül izlendi. Sonuç: MR enterografi, Crohn hastalığının takibinde, hastalığın aktif sürecindeki inflamasyonun, fibrostenoz evredeki striktürlerin, obstrüksiyonların, komplikasyonların belirlenmesinde ve tedavi seçeneğinin değerlendirilmesinde önemlidir. Gelecekte, mevcut MR sekansları ve yeni geliştirilen sekans teknikleriyle yapılacak geniş hasta katılımlı karşılaştırmalı çalışmalara ihtiyaç vardır. MR, ince bağırsağın diğer hastalıklarının değerlendirilmesinde de umut vericidir. Anahtar Kelimeler: MR enterografi, Crohn hastalığı, Mannitol Abstract Aim: We aim to evaluate the diagnostic efficiency of magnetic resonance (MR) enterography and mannitol %3 which have been gathered easily and provide good intestine distension. Methods: 42 patients whose ages are between 7 and 71 have been included in the project. MR enterography protocol has been done by 1.5 Tesla MRG (Magnetom Aera, Siemens Medical Solutions, Erlangen, Germany) device. Findings were compared to histopathological results obtained by surgery and fiberoptic endoscopy. Sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy rate have been calculated statistically. Results: Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy rate were calculated as 83%, 93%, 83%, 93% and 90%, respectively. Two patients with false negative results were evaluated as normal in the radiologic manner but pathologic investigation came as nonspecific inflammation. Pathologic investigation was recognized as ulcerative colitis for a patient with false positive result and in another patient with false positive result, invagination caused by a polypoid bulky mass due to the ectopic ...

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Radiation Doses from Small-Bowel Follow-Through and Abdominopelvic MDCT in Crohn's Disease

Cited by 175 publications

References 58 publications

SICUS and CEUS imaging in Crohn’s disease: an update

SICUS and CEUS imaging in Crohn’s disease: an update

Assessment of Organ Dose by Direct and Indirect Measurements for a Wide Bore X-Ray Computed Tomography Unit That Used in Radiotherapy

Diagnostic value of MR enterography for the assessment of small-bowel diseases

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