The influence of internal damping on the vibration of a piano soundboard is investigated using a Finite-Difference Time Domain (FDTD) physical model and experimental measurements. The damping constant of the model is varied according to a range similar to those found with measurements on a real grand piano at different production stages. With strong damping, a clear driving-point dependency of the forced string oscillation on the oscillation pattern of the soundboard is found. When decreasing the damping, this driving-point dependency is decreasing, nevertheless, it is still present. High damping, therefore, decreases soundboard vibration when strings drive the soundboard at the soundboard’s eigenfrequencies. However, such large damping increases soundboard vibrations when strings drive the soundboard at frequencies which are not eigenfrequencies. Therefore, strong damping smooths out the frequency response spectrum of an instrument. Extreme damping without any presence of distinct eigenmodes leads to a radiation of the strings sound spectrum without soundboard filtering. Low damping leads to a strong influence of the soundboard on the string’s radiated sound. Therefore, the amount of soundboard characteristics can be designed to alter internal damping process by choice of materials, including wood or varnish, and geometry. Additionally, damping reduces the presence of ’dead spots’, notes which are considerably lower in volume compared to other notes.