Radiation for MALT of the Submandibular Gland

Chadha, Juskaran; Teng, Marita S.; Teruya‐Feldstein, Julie; Bakst, Richard L.

doi:10.1155/2017/8397621

Cited by 1 publication

(1 citation statement)

References 25 publications

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“…The current study represents one of the largest series described in the literature and we have also observed asymptomatic swellings as the most common clinical presentation of the disease. In accordance to our results, MALT and follicular lymphomas seems to be frequent subtypes in this region, with several cases being previously reported ( 25 , 26 ). However, the occurrence of higher-grade variants, especially DLBCL NOS has already been demonstrated ( 10 , 27 ).…”

Section: Discussionsupporting

confidence: 93%

Lymphomas affecting the submandibular glands

Araújo,

Morais-Perdigão,

Lopez-de-Cáceres

et al. 2024

Med Oral

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Background Lymphomas affecting the submandibular glands are very uncommon and few reports are currently available in the literature. Therefore, the aim of the current study is to describe the clinical and microscopic features of an original series of lymphomas affecting the submandibular glands. Material and Methods The pathology files of two institutions were searched for lymphoma cases affecting the submandibular glands. The original hematoxylin and eosin, and immunohistochemical slides were revised by a pathologist for diagnosis confirmation following the revised 4th edition of the World Health Organization classification of tumours of haematopoietic and lymphoid tissues. Clinical data regarding age, sex, clinical manifestation, treatment, follow-up and status at last appointment were retrieved from the patients’ medical charts. Results During the period investigated, 16 cases were included in the study. Females predominated (10:6) with a mean age of 57.8 years-old. Tumors usually presented as asymptomatic swellings. MALT lymphoma represented the most common subtype, followed by diffuse large B cell lymphoma and follicular lymphoma. Three patients died, one of them affected by plasmablastic lymphoma, one by DLBCL and one by MALT lymphoma. Conclusions Low-grade B cell lymphomas predominate in the submandibular glands, but DLBCL and other subtypes may also be rarely diagnosed in this salivary gland. Key words: Lymphoma, salivary gland, submandibular gland, malt lymphoma, follicular lymphoma, diffuse large b cell lymphoma.

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