Radiation grafting of N-vinylpyrrolidone into silicone tubes. Synthesis of polymers with improved hemocompatibility and implantation tests in lambs

Modification of polysiloxane polymers for biomedical applications: a review

“…The largest number of studies on applications of radiation‐induced graft polymerization for obtaining medical polymers was carried out by Hoffman and co‐workers 40. 42–45 The radiation‐induced grafting of hydrophilic polymer systems, such as N ‐vinyl pyrolidone (NVP), 2‐hydroxyethyl methacrylate (HEMA), acrylamide (AAm), acrylic acid (AAc), glycidyl methacrylate (GMA), ethyleneglycol dimethacrylate (EGDMA) and ethyl methacrylate (EMA) onto silicone rubber, was studied 46–53. The grafting techniques in these studies exploit both simultaneous irradiation and pre‐irradiation methods.…”

Sequential interpenetrating polymer networks of poly(2‐hydroxyethyl methacrylate) and polydimethylsiloxane

“…Although many reports can be found in the literature dealing with silicone/hydrogel composites and hydrogel‐grafted silicones, 10–27 interpenetrating polymer network systems made from hydrogels and silicone rubber have received relatively little attention 28–31…”

Preparation of polymeric biomaterials with the aid of radiation-chemical methods

“…Another monomer which being vigorously employed for increasing biocompatibility is the highly hydrophilic monomer N-vinylpyrrolidone. 48,52,58,60,67,68,75,78 The radiationinduced grafting of N-vinylpyrrolidone is as a rule carried out by the direct method from its solutions in water, toluene, or methanol, using low radiation doses. As in the case of acrylamide, after the graft polymerisation of N-vinylpyrrolidone the hydrophilicity increases significantly with increasing amount of the grafted material.…”