Radiation Induced Angiosarcoma of the Breast: Case Series - Review at a Single Breast Screening Institution and Review of the Literature

Ashour, Omar; Fasih, Tarannum

doi:10.21767/2254-6081.100073

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…Ashour et al also described a painless lump and skin discolouration as presenting features. [4]. The presence of a palpable mass is a rare phenomenon, and our patient had a rapidly growing fungating mass with skin erosion and spontaneous bleeding which is unusual.…”

Section: Discussionmentioning

confidence: 69%

“…In 1907, Borman et al describes the first case of angiosarcoma of the breast, whereas the first case of radiationinduced secondary angiosarcoma was described Body et al in 1987 [4]. With the evolution of breast conservativation surgery, there is increased usage of adjuvant local radiation which is significant risk factor for soft tissue sarcomas, particularly angiosarcoma [3,5].…”

Section: Discussionmentioning

confidence: 99%

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Unusual Presentation of Bilateral Radiation-Induced Angiosarcoma of the Breast

Jayarajah

Nagodavithane

Basnayake

et al. 2020

Case Reports in Oncological Medicine

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Radiation-induced sarcoma of the breast is an iatrogenic malignancy that occurs secondary to radiotherapy, which is most commonly given following breast conservation surgery. It has an incidence of 3.2 per 1,000 patients at 15 years and is associated with a poor prognosis. We report a 62-year-old female with a history of bilateral breast conservation surgery and radiotherapy 5 years ago presenting with bilateral angiosarcoma. This case report highlights the importance of considering radiation-induced angiosarcoma of the breast as a differential diagnosis in a patient with recurrent breast neoplasms. The challenges in the management with recent evidence on new treatment modalities are discussed.

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Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Unusual Presentation of Bilateral Radiation-Induced Angiosarcoma of the Breast

Jayarajah

Nagodavithane

Basnayake

et al. 2020

Case Reports in Oncological Medicine

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“…Secondary angiosarcoma are more likely to be of high-grade (82%) compared to primary angiosarcoma [6]. Literature review shows many reports of secondary post-irradiation angiosarcoma in females to be hormone-receptor positive breast cancers under hormonal therapy [6, 7].…”

Section: Discussionmentioning

confidence: 99%

Secondary angiosarcoma in a hormone receptor negative breast cancer patient

Khanal

Chitrakar

Nepal

et al. 2019

Journal of Surgical Case Reports

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Post-irradiation angiosarcoma arising in the irradiated breast after breast‐conserving surgery is uncommon though being reported with increasing frequency. Such cases are reported mainly in hormone-receptor positive patients who had received hormonal therapy along with radiation. We describe a rare case of post-irradiation angiosarcoma in a 71-year-old hormone-receptor negative female who did not receive hormonal therapy.

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Non-hematological Malignancies in the Bone Marrow

Beham‐Schmid

Schmitt‐Graeff

2020

Essentials of Diagnostic Pathology

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Radiation Induced Angiosarcoma of the Breast: Case Series - Review at a Single Breast Screening Institution and Review of the Literature

Cited by 4 publications

References 19 publications

Unusual Presentation of Bilateral Radiation-Induced Angiosarcoma of the Breast

Unusual Presentation of Bilateral Radiation-Induced Angiosarcoma of the Breast

Secondary angiosarcoma in a hormone receptor negative breast cancer patient

Non-hematological Malignancies in the Bone Marrow

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