Radiation-induced lesions of the aorta.

Abstract

women were significantly higher. Only 4% of the men had raised serum T4 levels compared with 11 % of the women.5 These observations

Myocardial Infarction Following Radiotherapy for Hodgkin's Disease

“…There have been isolated reports in the medical literature of young patients treated for Hodgkin's disease with mediastinal irradiation suffering later from myocardial infarction (Prentice, 1965; Dollinger, Lavine and Foye, 1965, 1966; Cohn et al 1967; Stewart et al 1967; Huff and Sanders, 1972; McReynolds, Gold and Roberts, 1976; Rodgers, 1976; Ali et al 1976; Døssing et al 1977). The characteristic findings are coronary artery disease in the absence of atherosclerosis in other systemic arteries, including the aorta.…”

“…There have been isolated reports in the medical literature of young patients treated for Hodgkin's disease with mediastinal irradiation suffering later from myocardinal infarction (Prentice, 1965;Foye, 1965, 1966;Stewart et al 1967;Huff and 'Sanders, 1972;McReynolds, Gold and Roberts, 1976;Rodgers, 1976;Ali et al 1976;Dessing et al 1977). The characteristic findings are coronary artery disease in the absence of atherosclerosis in other systemic arteries, including the aorta The typical histological changes are severe thickening of the coronary arteries by both intimal and adventitial fibrous proliferation and epicardial fibrosis (Stewart et al 1967;Me-Reynolds, Gold and Roberts, 1976), and fibromuscular proliferation interior to the internal elastic membrane (Dollinger, Lavine and Foye, 1965).…”