Radiation-induced malignant fibrous histiocytoma of the neck in a patient with laryngeal carcinoma

Haberal, İlknur; Samim, Erdal; Astarci, Müzeyyen; Özeri, Cavit

doi:10.1053/ajot.2001.22579

Cited by 12 publications

(12 citation statements)

References 8 publications

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“…A poor prognosis can be expected because extensive removal of the tumor is not easily accomplished. Owing to its high rate of recurrence and metastasis, early detection and complete excision of the tumor are necessary [32,33].…”

Section: Discussionmentioning

confidence: 99%

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Radiation-induced malignant fibrous histiocytoma of the maxilla

et al. 2011

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Malignant fibrous histiocytoma (MFH) originates from primitive mesenchymal cells and has the capacity for dual histiocytic and fibroblastic differentiation. We report on an MFH of the left maxilla that developed in a 79-year old woman 20 years after surgery and radiation for squamous cell carcinoma (SCC). Postoperative radiotherapy with 70 Gy was administered for a primary neoplasm of SCC of the left maxilla to a localized field through two lateral ports. This secondary neoplasm arose at the site of tumor resection (partial maxillectomy) within the irradiated field, and was resected. The development of sarcomas is a recognized complication of radiation therapy. The final diagnosis after the operation was MFH. The patient died of tumor recurrence at the skull base and within the cranium, 19 months after the operation. Radiation-induced sarcoma is well known, but radiation-induced MFH is relatively rare in the head and neck region. The details of this case are presented with a review of literature.

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Section: Discussionmentioning

confidence: 99%

“…To detect a secondary tumor as early as possible, patients treated with irradiation need careful long-term follow, including CT and MRI when warranted, for many years [33][34][35].…”

Section: Discussionmentioning

confidence: 99%

Radiation-induced malignant fibrous histiocytoma of the maxilla

et al. 2011

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“…[30][31][32][33] Radiation-induced intestinal MFH has also been described. 4 The chronic postoperative repair process is thus considered to possibly be a promoting factor in the tumorigenesis of this neoplasm, on the analogy of malignant fibrous histiocytoma arising at different sites.…”

Section: Discussionmentioning

confidence: 98%

Primary Malignant Fibrous Histiocytoma of the Small Intestine Presenting as an Intussusception: Report of a Case

Kotan¹,

Kosem²,

Alıcı³

et al. 2002

Surgery Today

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Malignant fibrous histiocytoma occurs most commonly in the extremities and trunk, but rarely in the visceral organs. Malignant fibrous histiocytoma of the small intestine is an extremely rare condition. To our knowledge, only ten cases of primary tumors involving the small intestine have been described up to now. Among them only one case has been reported to lead to intussusception. This case report documents the appearance of a storiform-pleomorphic type primary malignant fibrous histiocytoma of the ileum, which led to intussusception, in a 58-year-old man with a 3-month history of dyspepsia, weight loss, general fatigue, and nonspecific abdominal pain. The patient was well with no sign of disease at 8 months after surgery. The clinical and pathologic characteristics of malignant fibrous histiocytoma of the small intestine as found in the literature are also reviewed.

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“…Squamous cell carcinoma is the most common histologic type of radiation-induced malignancy [1,[4][5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

“…The overall incidence of PRS is less than 1% for patients with cancer who are treated with radiation and survive 5 years [2]. Head and neck lesions account for 10% of PRSs [1,7,11]. In the literature few cases have been reported.…”

Section: Introductionmentioning

confidence: 99%