2021
DOI: 10.17816/brmma65173
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Radiation-induced oral mucositis — radiation-induced oral mucositis: pathogenesis, risk factors, clinical manifestations, prevention, and treatment

Abstract: This study presents the modern concepts of pathogenesis, risk factors, etiology, clinical manifestations, prevention, and treatment of oropharyngeal mucositis, one of the main complications of radiation therapy for head and neck region cancer. The leading role in the mechanisms of disease development belongs to rapidly dividing cells of the basal layer of the oropharyngeal mucous membrane. This damage is due to both direct (excitation and ionization) and indirect (accumulation of active oxygen and nitrogen com… Show more

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“…Increased efficiency in screening may be achieved through the application of cutting-edge techniques as well as risk-adapted screenings processes that include excellent risk predictive model and screening processes. Our study lays new ground work for the creation and refinement of CRC prevention measures [ 4 ]. The treatment protocol for colorectal cancer is derived from the National Comprehensive Cancer Network [ 5 ], European Society for Medical Oncology [ 6 ], and Chinese Society of Clinical Oncology guideline.…”
Section: Introductionmentioning
confidence: 99%
“…Increased efficiency in screening may be achieved through the application of cutting-edge techniques as well as risk-adapted screenings processes that include excellent risk predictive model and screening processes. Our study lays new ground work for the creation and refinement of CRC prevention measures [ 4 ]. The treatment protocol for colorectal cancer is derived from the National Comprehensive Cancer Network [ 5 ], European Society for Medical Oncology [ 6 ], and Chinese Society of Clinical Oncology guideline.…”
Section: Introductionmentioning
confidence: 99%