Radiation-Induced Sarcoma on 18F-FDG PET/CT After Treatment of Gorham-Stout Disease of the Maxilla

Rodriguez-Vazquez, Jose R.; Chandra, Srinivasa R.; Albertson, Megan; Hansen, Neil J.; Johnson, Craig M.

doi:10.1097/rlu.0000000000002761

Cited by 7 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our patient is young and further disease progression or development of treatment-related toxicity could have devastating consequences. Furthermore, radiation-induced sarcoma after management of skull base GSD has been reported, placing an importance in reducing the total treatment volume 21 . Proton therapy has emerged as another modality to deliver RT for skull base tumors while minimizing integral dose to organs at risk 22,23 .…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

“…Furthermore, radiation-induced sarcoma after management of skull-base GSD has been reported, placing importance on reducing the total treatment volume. 21 Proton therapy has emerged as another modality to deliver RT for skull base tumors while minimizing integral dose to organs at risk. 22 , 23 Therefore, we recommend that conformal RT techniques (IMRT or proton therapy) be considered for the treatment of skull-base GSD refractory to surgical and medical management.…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

See 1 more Smart Citation

A Case of Gorham-Stout Disease of the Skull Base Treated With Intensity Modulated Radiation Therapy

Roy

Andruska

Brenneman

et al. 2022

Advances in Radiation Oncology

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Section: Discussion and Literature Reviewmentioning

confidence: 99%

A Case of Gorham-Stout Disease of the Skull Base Treated With Intensity Modulated Radiation Therapy

Roy

Andruska

Brenneman

et al. 2022

Advances in Radiation Oncology

View full text Add to dashboard Cite

show abstract

“…Exclusive involvement of maxilla is rarely described in the literature. Only 4 cases are reported involving the maxilla till date and ours is the 5 th case ( Table 1 ) [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] . The remaining 4 cases described in Table 1 showed multicentric involvement of other craniofacial bones.…”

Section: Discussionmentioning

confidence: 99%

Gorham's disease of the maxilla – A rare case report with literature overview

Patil

Konidena

2021

Radiology Case Reports

View full text Add to dashboard Cite

Gorham's disease is a rare condition characterized by progressive osteolysis of bone ultimately resulting in the total disappearance of bone. The etiology is unknown and the disease predominantly affects the pelvis, humerus, and axial skeleton. Because of its unusual, ambiguous presentation and rare occurrence, the disorder goes unrecognized and is often masqueraded by other disorders. The diagnosis of this disorder is by exclusion. About 50 cases of Gorham's disease involving the maxillofacial region are reported to date and most of them involve the mandible. Exclusive involvement of maxilla is documented in only 4 cases. We report an exceptional case of Gorham's disease of the maxilla in a 68-year-old male patient presenting with chronic pain and masquerading as an odontogenic infection.

show abstract

“…German Cooperative Group on Radiotherapy for Benign Diseases concluded that radiation therapy can effectively prevent progression of GSD in 80% of case, and advocated dose range of 30 to 45 Gy at 1.8 Gy to 2 Gy per fraction [37]. Of note, radiation could provoke serious side effects, like secondary malignancy and growth restriction in children and adolescents who received high-dose therapy [11, 38].…”

Section: Discussionmentioning

confidence: 99%

Gorham-Stout disease of the malleolus: a rare case report

Zheng

Tang

et al. 2019

BMC Musculoskelet Disord

View full text Add to dashboard Cite

BackgroundGorham-Stout disease, also known as vanishing bone disease, idiopathic massive osteolysis, is a rare entity of unknown etiopathology. This disease is characterized by destruction of osseous matrix and proliferation of lymphatic vascular structures and associated with massive regional osteolysis. It has a variable clinical presentation and is commonly considered as a benign disease with a progressive tendency and an unpredictable prognosis. The diagnosis is made by exclusion and based on combination with histological, radiological, and clinical features. Despite that several therapeutic options have shown certain efficacy, the effective treatment still remains controversial and there is no standard treatment to be recommended.Case presentationA previously healthy 40-year-old man presented with right lateral malleolus pain after an ankle sprain and was referred to our hospital. The radiographs indicated rapid massive bone destruction in the distal right lateral malleolus with an unclear margin. Based on the combination with histological, radiological, and clinical features, the diagnosis of Gorham-Stout disease was made. Considering that the residual function of malleolus had to be protected, prior bisphosphonate was used to control the progression of lesion, followed by surgical resection and biological reconstruction with autologous fibular bone grafting. The patient was followed up 8 years after surgery, he presented without progression and recurrence.ConclusionsWe depict a case of Gorham-Stout disease at the right lateral malleolus and was successfully controlled by medication and surgical intervention. Based on the prior effective medical treatment, resection with biological reconstruction is a useful approach to treat Graham-Stout disease in bone.

show abstract

Radiation-Induced Sarcoma on 18F-FDG PET/CT After Treatment of Gorham-Stout Disease of the Maxilla

Cited by 7 publications

References 7 publications

A Case of Gorham-Stout Disease of the Skull Base Treated With Intensity Modulated Radiation Therapy

A Case of Gorham-Stout Disease of the Skull Base Treated With Intensity Modulated Radiation Therapy

Gorham's disease of the maxilla – A rare case report with literature overview

Gorham-Stout disease of the malleolus: a rare case report

Contact Info

Product

Resources

About