Radiation pneumonitis in patients treated for breast cancer

Rothwell, R.I.; Kelly, S.A.; Joslin, C. A.

doi:10.1016/s0167-8140(85)80056-6

Cited by 114 publications

(36 citation statements)

References 5 publications

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“…In the past years several authors have addressed the problem of radiation-induced lung damage in breast cancer patients (1)(2)(3)(4)(5)(6). Though most of the patients do not suffer from clinical side-effects from the lungs after standard radiotherapy, cough and dyspnoe are known to cause major distress among patients suffering from radiationinduced pneumonitis.…”

mentioning

confidence: 99%

Influence of Radiation Therapy on Lung Tissue in Breast Cancer Patients: CT-assessed density changes 4 years after completion of radiotherapy

1995

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mentioning

confidence: 99%

Influence of Radiation Therapy on Lung Tissue in Breast Cancer Patients: CT-assessed density changes 4 years after completion of radiotherapy

1995

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“…Sternoradiation has known complications, such as pneumotitis. 12 Furthermore, three of the 30 patients (10%) had metastases only to the IMN basin. This result indicates a somewhat higher IMN metastatic frequency without axillary metastases than those some authors 2,5,13 have reported.…”

Section: Discussionmentioning

confidence: 97%

Utility of Internal Mammary Lymph Node Removal When Noted by Intraoperative Gamma Probe Detection

et al. 2001

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“…To account for the complex organ motion, we have previously investigated a few deformable models, 6,7 and adopted the free-form spline model ͑BSpline͒ in this work. 8 Its simplicity and yet accuracy make it a preferred tool for clinical applications. [9][10][11] In this model, a lattice of user-defined nodes is overlaid on the image.…”

Section: Deformable Registration For Phase Imagesmentioning

confidence: 99%

“…Conventional radiotherapy for breast cancer utilizes two opposed tangential fields (OTF) with either uniform or wedged photon beams [1][2][3][4] , and often presents problems related to breast dose inhomogeneity and relatively high doses to the ipsilateral lung and heart, because certain volume of the ipsilateral lung and, in the case of the left breast, part of the heart is inevitably included in the tangential fields. As a consequence, breast irradiation has been associated with a number of potential complications [5][6][7][8] , including radiation induced pneumonitis, cardiac toxicity, rib fracture, arm edema, severe breast or chest wall fibrosis, soft tissue or bone necrosis, and radiation induced secondary cancer. Intensity Modulated Radiation Therapy (IMRT) is a highly promising technology that can potentially overcome these problems 9-14 .…”

mentioning

confidence: 99%

Multiple Aperture Radiation Therapy (MART) to Breast Cancer

Li¹

2005

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Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 5e. TASK NUMBER 5f. WORK UNIT NUMBER REPORT DATE 01-11-2005 REPORT TYPE Annual Summary DATES COVERED PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBERStanford University Stanford, CA 94305 SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR'S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 SPONSOR/MONITOR'S REPORT NUMBER(S) DISTRIBUTION / AVAILABILITY STATEMENTApproved for Public Release; Distribution Unlimited SUPPLEMENTARY NOTESOriginal contains colored plates: ALL DTIC reproductions will be in black and white. ABSTRACTCompared with conventional methods for breast cancer RT such as opposed tangential fields (OTF), modern IMRT provides unprecedented potential to deliver 3D-dose distributions with superior tumor conformality and normal tissue spare. In practice, however, the current IMRT process deviates significantly from the conventional approach and requires considerable costs of the time and health care. The complexity of the treatment and deliver procedure make this technology problematic for the breast radiotherapy. We have carried out a systematic study on a new solution, which is a hybrid of the advantages of the IMRT and OTF, termed as multiple aperture radiotherapy (MART). The efficiency in dose shaping and simplicity in dose delivery make it a perfect choice for breast cancer treatment.A number of important milestones have been accomplished, which include (i) developed an efficient optimization method for MART inverse planning; (ii) implemented MART in a clinic environment for breast treatment; (iii) proposed a gated IMRT/MART based on the cutting-edge technology of 4D CT imaging; (iv) established a robust technique for low-dose 4D CT acquisition to reduce the risks of radiation-induced cancer. It is expected these tools will greatly facilitate the imaging, planning, delivery, and quality assurance of breast radiation treatment. Conventional radiotherapy for breast cancer utilizes two opposed tangential fields (OTF) with either uniform or wedged photon beams [1][2][3][4] , and often presents proble...

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Radiation pneumonitis in patients treated for breast cancer

Cited by 114 publications

References 5 publications

Influence of Radiation Therapy on Lung Tissue in Breast Cancer Patients: CT-assessed density changes 4 years after completion of radiotherapy

Influence of Radiation Therapy on Lung Tissue in Breast Cancer Patients: CT-assessed density changes 4 years after completion of radiotherapy

Utility of Internal Mammary Lymph Node Removal When Noted by Intraoperative Gamma Probe Detection

Multiple Aperture Radiation Therapy (MART) to Breast Cancer

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