Radiation risk assessment in neonatal radiographic examinations of the chest and abdomen: a clinical and Monte Carlo dosimetry study

Makri, Triantafillia; Yakoumakis, E.; Papadopoulou, Despina; Gialousis, G.; Theodoropoulos, V; Sandilos, P.; Georgiou, Evangelos

doi:10.1088/0031-9155/51/19/019

Cited by 39 publications

(19 citation statements)

References 31 publications

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“…39,40 Second, the observed association might indicate that the neonatal treatment provided to newborns with a low Apgar score at 5 min could increase the risk of a subsequent Wilms tumor. [41][42][43] Third, it might also reflect reverse causation insofar that the yet undiagnosed Wilms tumor or predisposure to develop a Wilms tumor lead to symptoms related to a low Apgar score. The positive association with Apgar score, however, was not restricted only to young cases but seen in all age groups.…”

Section: Discussionmentioning

confidence: 99%

Birth characteristics and Wilms tumors in children in the Nordic countries: A register‐based case–control study

Schüz

Schmidt

Kogner

et al. 2011

Intl Journal of Cancer

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Little is known about causes of Wilms tumor. Because of the young age at diagnosis, several studies have looked at various birth characteristics. We conducted a registry-based case-control study involving 690 cases of Wilms tumor aged 0-14 years, occurring in Denmark, Finland, Norway or Sweden during 1985, individually matched to five controls drawn randomly from the Nordic childhood population. Information on birth characteristics was obtained from the population-based medical birth registries. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) using conditional logistic regression analysis. We observed a distinct association between Wilms tumor and high birth weight (4 kg) for girls (OR 1.97, CI 1.50-2.59) but not for boys (1.04, 0.78-1.38); overall, the OR was 1.43 (1.17-1.74). Among girls, risk increased by 28% (15-42%) per 500 g increase in birth weight. Large-for-gestational age girls also had a higher risk (2.48, 1.51-4.05), whereas no effect was seen for boys (1.12, 0.60-2.07). An association was seen with Apgar score at 5 min < 7 for both sexes combined (5.13, 2.55-10.3). ORs close to unity were seen for parental age and birth order. In our large-scale, registry-based study, we confirmed earlier observations of an association between high birth weight and risk of Wilms tumor, but we found an effect only in girls. The higher risk of infants with low Apgar score might reflect hypoxia causing cell damage, adverse side effects of neonatal treatment or reverse causation as low Apgar score might indicate the presence of a tumor.Renal tumors in children are rare. Its major subtype, Wilms tumor or nephroblastoma, constituting >95% of all childhood renal tumors, is an embryonal malignancy arising from remnants of the immature kidney.

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Section: Discussionmentioning

confidence: 99%

Birth characteristics and Wilms tumors in children in the Nordic countries: A register‐based case–control study

Schüz

Schmidt

Kogner

et al. 2011

Intl Journal of Cancer

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“…Table 3 shows the E levels of various conventional radiologic procedures in adults, children, and neonates. 6,7,10,17,[30][31][32] This comparison is only an approximation, because even for the same radiologic procedure, dose levels are directly related to variations in equipment and depend on age. Nevertheless, conventional radiographs impose a relatively low level of radiation exposure.…”

Section: Discussionmentioning

confidence: 99%

“…4 Tables 7 and 8 show the cancer mortality risk for our cohort of VLBW infants, on the basis of the highest risk level of 13 ϫ 10 Ϫ2 /Sv Ϫ1 , findings similar to those previously reported. 6,7,9,21,40 We also determined risk factors for preterm infants associated with radiographic exposure of specific body regions. 7,10,31 Cancer mortality rates after radiation exposure during childhood (age not further classified) have been reported to be 1:1 000 000 for a thorax radiograph (E Ͻ50 Sv) and 1:100 000 for an abdominal radiograph (E Ͻ100 Sv).…”

Section: Discussionmentioning

confidence: 99%

“…The International Commission on Radiologic Protection (ICRP) has defined the concept of effective dose (E), 4 which has become an accepted method for estimating dose and associated risks in diagnostic radiology. 5 There have been few international comparisons of E for preterm, [6][7][8] , and extremely low birth weight (ELBW) infants. 8,10 To our knowledge, this is the first German study on the estimation of E in a large number of VLBW and ELBW infants.…”

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confidence: 99%

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Radiation Exposure in 212 Very Low and Extremely Low Birth Weight Infants

et al. 2009

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“…This emphasizes the importance of the as low as reasonably achievable (ALARA) concept. At present, cancer induction is a stochastic risk with a linear-no-threshold dose model; therefore, reduced exposure to radiation decreases the risk of the development of cancer, such as leukemia, in subjects [21]. To resolve this, the ESD must be reduced while maintaining the image quality.…”

Section: Discussionmentioning

confidence: 99%

Development of Portable Digital Radiography System with a Device for Monitoring X-ray Source-Detector Angle and Its Application in Chest Imaging

Kim

Heo

Jeong

et al. 2017

Sensors

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This study developed a device measuring the X-ray source-detector angle (SDA) and evaluated the imaging performance for diagnosing chest images. The SDA device consisted of Arduino, an accelerometer and gyro sensor, and a Bluetooth module. The SDA values were compared with the values of a digital angle meter. The performance of the portable digital radiography (PDR) was evaluated using the signal-to-noise (SNR), contrast-to-noise ratio (CNR), spatial resolution, distortion and entrance surface dose (ESD). According to different angle degrees, five anatomical landmarks were assessed using a five-point scale. The mean SNR and CNR were 182.47 and 141.43. The spatial resolution and ESD were 3.17 lp/mm (157 μm) and 0.266 mGy. The angle values of the SDA device were not significantly difference as compared to those of the digital angle meter. In chest imaging, the SNR and CNR values were not significantly different according to the different angle degrees. The visibility scores of the border of the heart, the fifth rib and the scapula showed significant differences according to different angles (p < 0.05), whereas the scores of the clavicle and first rib were not significant. It is noticeable that the increase in the SDA degree was consistent with the increases of the distortion and visibility score. The proposed PDR with a SDA device would be useful for application in the clinical radiography setting according to the standard radiography guidelines.

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Radiation risk assessment in neonatal radiographic examinations of the chest and abdomen: a clinical and Monte Carlo dosimetry study

Cited by 39 publications

References 31 publications

Birth characteristics and Wilms tumors in children in the Nordic countries: A register‐based case–control study

Birth characteristics and Wilms tumors in children in the Nordic countries: A register‐based case–control study

Radiation Exposure in 212 Very Low and Extremely Low Birth Weight Infants

Development of Portable Digital Radiography System with a Device for Monitoring X-ray Source-Detector Angle and Its Application in Chest Imaging

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