Ag 2 O-MoO 3 -V 2 O 5 -TeO 2 (AMVT) glasses were reported by means of their optical properties such as polarizability, optical transmission, and optical basicity. Moreover, the photon attenuation properties were explored by using FLUKA simulation code for energies up to 1.275 meV. From the optical study, it was noted that the molar polarizability (α Mol. ) decreased from 11.8630 × 10 -24 to 9.4846 × 10 -24 cm 3 , while the optical transmission increased from 0.5498 to 0.5976 as the Ag 2 O concentration increased from 0 to 25 mol%. From the photon attenuation study, the maximum values of µ/ρ (MAC, mass attenuation coefficient) were observed at 0.284 meV. Such those values were 0.1501, 0.1525, 0.1549, 0.1572, 0.1593 and 0.1616 cm 2 /g for AMVT1, AMVT2, AMVT3, AMVT4, AMVT5 and AMVT6, respectively. From the view of practical application, it is found that the HVL values of the AMVT glasses are evidently lower than those of ordinary concrete and RS-253-G18 commercial glass.