“…Cross-linked networks of synthetic polymers such as polyethylene oxide (PEO) (Khoylou & Naimian, 2009), polyvinyl pyrollidone (PVP) (Razzak et al, 2001), polylactic acid (PLA) (Palumbo et al, 2006), , polyacrylic acid (PAA) (Onuki et al, 2008), polymethacrylate (PMA) (Yang et al), polyethylene glycol (PEG) (Singh et al), or natural biopolymers (Coviello et al, 2007) such as alginate, chitosan, carrageenan, hyaluronan, and carboxymethyl cellulose (CMC) have been reported. The various preparation techniques adopted are physical crosslinking (Hennink & Nostrum, 2002), chemical cross-linking (Barbucci et al, 2004), grafting polymerisation (Said et al, 2004), and radiation cross-linking (Fei et al, 2000;Liu et al, 2002b).…”