Radiation-synthesized polysaccharides/polyacrylate super water absorbents and their biodegradabilities

Relleve, Lorna S.; Aranilla, C.T.; Barba, Bin Jeremiah D.; Gallardo, Alvin Kier R.; Cruz, Veriza Rita C.; Ledesma, Carlene Rome M.; Nagasawa, Naotsugu; Abad, Lucille V.

doi:10.1016/j.radphyschem.2019.108618

Cited by 22 publications

(7 citation statements)

References 36 publications

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“…Both polymers exhibited decreased swelling with increasing absorbed dose (Figure 2), correlated to an increasing degree of crosslinking, which was confirmed by the nonextractable gel fractions. Higher crosslinking restricts the diffusion of water into the hydrogel and limits the surface available for hydrogen bonding 37,38 . This was also reflected during gel expansion at low doses and constriction at higher doses upon swelling in PBS.…”

Section: Discussionmentioning

confidence: 99%

Simple fabrication of gelatin–polyvinyl alcohol bilayer hydrogel with wound dressing and nonadhesive duality

Barba¹,

Oyama

Taguchi

2021

Polymers for Advanced Techs

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Persistence of postoperative adhesions can lead to fatal complications in patients undergoing abdominal and pelvic surgery, even years after the operation. Thus, effective barrier materials are majorly required for reducing peritoneal adhesions. In the present study, a novel bilayer hydrogel achieving both wound dressing and antiadhesion capabilities was developed from gelatin and polyvinyl alcohol (PVA) using simultaneous reagent‐free radiation‐induced crosslinking with γ‐rays. The gelatin presents wound dressing ability, whereas the PVA reveals nonadhesive capability. Layers were sufficiently bonded via a small “mixed” interface, as supported via scanning electron microscopy and 2D‐infrared spectroscopy. Cell culture of 3T3‐Swiss fibroblasts exhibited good cell proliferation on the gelatin, which can further facilitate tissue regeneration, whereas PVA exhibited limited cell adhesion and growth. Cell viability suggests that the bilayer is noncytotoxic. Enzymatic degradation test indicated a complete breakdown of gelatin by proteases, leaving the PVA layer mostly intact. These in vitro assessments of the developed bilayer hydrogel demonstrated its potential as a novel medical material with wound dressing and nonadhesive duality.

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Section: Discussionmentioning

confidence: 99%

Simple fabrication of gelatin–polyvinyl alcohol bilayer hydrogel with wound dressing and nonadhesive duality

Barba¹,

Oyama

Taguchi

2021

Polymers for Advanced Techs

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“…At 185-315 °C, the decarboxylation and depolymerization of both the PAA and CMHA main chains of the hydrogel blends occur [4,12]. The observed mass losses greater than 315 °C were potentially from crosslinked CMHA chains, CMHA-PAA chains, andPAA chains with different crosslink densities formed after irradiation [13]. The thermograms of the CMHA-PAA and CMHA-Carbopol hydrogels without soluble fractions are shown in Figure 4.…”

Section: Ft-ir and Tga Analysismentioning

confidence: 99%

Gel Properties of Carboxymethyl Hyaluronic Acid/Polyacrylic Acid Hydrogels Prepared by Electron Beam Irradiation

Gallardo¹,

Relleve²,

Silos³

2021

The 2nd International Online Conference on Polymer Science—Polymers and Nanotechnology for Industry 4.0

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Semi-synthetic hydrogels made of carboxymethyl hyaluronic acid (CMHA) and polyacrylic acid (PAA) were synthesized using electron beam irradiation. CMHA, with a degree of substitution of 0.87 and a molecular weight of 149 kDa, was mixed with linear PAA and slightly crosslinked PAA (Carbopol). The equal weight ratio of the CMHA-Carbopol blends (10% CMHA, 10% Carbopol) was successfully crosslinked, even at a low irradiation dose of 20 kGy, producing a hydrogel with 60% gel fraction and 430 g/g degrees of swelling. The gel properties of this formulation showed good stability when exposed in PBS (pH 7.4) at 37 °C. Furthermore, the FT-IR spectra of the 10% CMHA, 10% Carbopol blends showed an increase in peak intensity at 1405 cm−1 due to the neutralization reaction between the COOH and COO- groups of PAA and CMHA polymers. The interaction effects between the concentration of CMHA and PAA and varying irradiation doses in the gel properties in CMHA-PAA hydrogels will be explored in a future study. Radiation crosslinking of biocompatible CMHA to other synthetic polymers, such as PAA, provides a cleaner method of producing biomaterials with tunable properties that are ideal for pharmaceutical, medical, and cosmetic applications.

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“…Depolymerized carrageenan through gamma-irradiation is a polysaccharide and a stimulant that has been a subject for researches in the recent years (Naeem et al, 2014;Abad et al, 2011Abad et al, , 2016. Carrageenan is considered to be potent elicitors of plant defense responses (Mercier et al, 2001;Kloareg & Quatrano, 1998;Potin et al 1999;Ning et al, 2003), as plant growth promoters (Hien et al, 2000;Kume et al, 2002;Naeem et al, 2011Naeem et al, , 2012Naeem et al, , 2014, inducer of seed germination (Hien et al, 2000), shoot elongation (Hien et al, 2000& Natsume et al, 1994, root growth (Iwasaki & Matsubara, 2000), flower production (Darvill et al, 1992), antimicrobial activity (Luan, 2003), and have prominent effects on the physiological activities of plant (Abad et al, 2009;Bi et al, 2010;Kume et al, 2002;Naeem et al, 2011;Relleve et al, 2000Relleve et al, , 2005. This is commercially known as carrageenan plant growth promoter (CPGP).…”

Section: Introductionmentioning

confidence: 99%

Growth and yield response of pepper (Capsicum annuum L.) to foliar application of carrageenan plant growth promoter

Guzman,

Valdez

2024

IJSTEM

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The study determined the growth and yield response of pepper (Capsicum annuum L.) to varying concentrations and frequencies of Carrageenan Plant Growth Promoter (CPGP). The study was set-up in a split-plot randomized complete block design with three replications. The three varying application frequencies were designated as main-plots, and the four concentrations of CPGP, as sub-plots. Peppers applied with 120 ppm and two to three times application of CPGP significantly matured earlier based on number of days to flowering and number of days to first priming. The same treatment combination resulted in significantly taller plants and higher number of lateral shoots. In terms of yield, however, CPGP at 120 ppm applied three times gave significantly higher number and heavier weight of fruits. The concentration of 120 ppm CPGP applied thrice in growing pepper is shown in the study to be the best treatment combination, thus, is recommended to improve the growth and increase the yield of pepper.

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Radiation-synthesized polysaccharides/polyacrylate super water absorbents and their biodegradabilities

Cited by 22 publications

References 36 publications

Simple fabrication of gelatin–polyvinyl alcohol bilayer hydrogel with wound dressing and nonadhesive duality

Simple fabrication of gelatin–polyvinyl alcohol bilayer hydrogel with wound dressing and nonadhesive duality

Gel Properties of Carboxymethyl Hyaluronic Acid/Polyacrylic Acid Hydrogels Prepared by Electron Beam Irradiation

Growth and yield response of pepper (Capsicum annuum L.) to foliar application of carrageenan plant growth promoter

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