Radiation technology in medicine: Part 2. Using isotopes in nuclear medicine

World Trends in the Application of Accelerators for the Production of Basic Isotopes for Nuclear Medicine

“…The production of other isotopes that can be used in modern nuclear medicine [6,36,50], taking into account a small part of their production in terms of cost to the isotopes discussed above, does not currently require the use of specially designed accelerating systems. Therefore, it makes no sense to discuss the advantages of using one or another accelerator for their production.…”

“…With the help of electron accelerators, the reconstruction of the existing methods of obtaining 99 Mo can be carried out with much lower costs. Quite a lot of works have been devoted to the development of isotope production technology [6,10,[17][18][19][26][27][28][29][30][31][32][33][34][35]. The production of an isotope using electron accelerators is possible only using the reactions 238 U (γ, F) 99 Mo and 100 Mo (γ, n) 99 Mo.…”

“…Nuclear medicine is industry of medicine, using radionuclidess for diagnostics and treatment of illnesses. The use of radioactive isotopes for the diagnosis and treatment of cancer and other diseases is widely used in modern medical practice [1][2][3][4][5][6][7].…”

Novel Immuno-PET Medical Radionuclides

“…На заре ПЭТ использовались коротко-и ультракороткоживущие изотопы 15 O, 13 N, 11 C, 18 F [14]. Комбинирование монАТ и излучателей позитронов требует соответствия между биологическим периодом полураспада белка и физическим периодом полураспада радионуклида для достижения оптимального уровня сигнал/шум в опухоли [15,16].…”

Optimization of "Glucose 11c" Pharmaceutical Production on the Beam of Electron Accelerator

“…All these isotopes are obtained using nuclear reactions at cyclotrons [4,5]. The same isotopes can be obtained using electron accelerators and photonuclear reactions.…”