2009
DOI: 10.1007/s00066-009-1968-x
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Radiation Therapy for Prevention of Heterotopic Ossification about the Elbow

Abstract: Pre- or postoperative RT is effective for prevention of HO about the elbow joint and can be recommended as an integral component of interdisciplinary treatment in complicated elbow fractures. At this, the use of MEPS has proven to be a feasible method for evaluation of the functional outcome.

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Cited by 26 publications
(24 citation statements)
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“…RT is known to be a safe and effective treatment option for the management of a variety of benign diseases of the locomotor system [11,[15][16][17]28]. A general patterns-of-care study executed in German RT departments revealed that annually more than 20,000 patients undergo RT for benign disorders of whom approximately 1,000 are treated for hyperproliferative disorders [33].…”
Section: Discussionmentioning
confidence: 99%
“…RT is known to be a safe and effective treatment option for the management of a variety of benign diseases of the locomotor system [11,[15][16][17]28]. A general patterns-of-care study executed in German RT departments revealed that annually more than 20,000 patients undergo RT for benign disorders of whom approximately 1,000 are treated for hyperproliferative disorders [33].…”
Section: Discussionmentioning
confidence: 99%
“…RT is known to be effective in a large variety of degenerative and hyperproliferative benign conditions affecting the skeletal system [1,4,9,[16][17][18], but knowledge of the value of RT in GSS is limited to several case reports and studies including a small number of patients. The endothelial cells of the abnormal vessels and proliferating capillaries are assumed to be the radiobiological target [3,13].…”
Section: Discussionmentioning
confidence: 99%
“…Demzufolge wird als vorrangiger Mechanismus der RT eine Obliteration abnormaler, zuführender Gefäße diskutiert, wobei die Endothelzellen dieser Gefäße als Zielstruktur angesehen werden [6,14,19]. Wenngleich die genauen Mechanismen der RT nach wie vor nicht geklärt sind, können Hämangiome dennoch durch eine Strahlentherapie ähnlich erfolgreich behandelt werden wie zahlreiche andere Entitäten nichtmaligner Erkrankungen [2,4,10,17,18,23,27,31] worden waren, eine signifikant bessere Symptomkontrolle bei Gesamtdosen zwischen 36 und 40 Gy ermittelten [29]. Basierend auf diesen Ergebnissen ist der Einsatz von Gesamtdosen von mindestens 34 Gy zu empfehlen.…”
Section: Diskussionunclassified