2021
DOI: 10.1016/j.gore.2021.100808
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Radiation therapy for vaginal and perirectal lesions in recurrent ovarian cancer

Abstract: Highlights Radiation to isolated vaginal and perirectal ovarian cancer recurrences provides effective in-field control. Complete response of targeted lesions after radiation was 88%. Radiation increased the chemotherapy-free interval without associated grade 3/4 toxicities. Platinum sensitivity prior to radiation may be associated with improved overall survival.

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Cited by 2 publications
(2 citation statements)
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“…Radiation therapy has a role as localized treatment to treat ovarian cancer patients with locally recurrent vaginal or perirectal lesions. The role of this treatment modality remains unclear, though we hypothesize that these patients may be treated locally and gain long-term survival benefits [ 82 ].…”
Section: Discussionmentioning
confidence: 99%
“…Radiation therapy has a role as localized treatment to treat ovarian cancer patients with locally recurrent vaginal or perirectal lesions. The role of this treatment modality remains unclear, though we hypothesize that these patients may be treated locally and gain long-term survival benefits [ 82 ].…”
Section: Discussionmentioning
confidence: 99%
“…However, in case of oligometastasis (especially vaginal/perirectal lesions and/or in lymph nodes) in heavily pretreated patients, intensity-modulated radiation therapy (IMRT) with additional high-dose brachytherapy could be proposed. A small retrospective study series showed that this approach is safe and provides long-term control of the irradiated region (69,70).…”
Section: Radiotherapymentioning
confidence: 99%