Radiation Therapy in Bronchogenic Carcinoma

Slawson, Robert G.; Scott, Ralph M.

doi:10.1148/132.1.175

Cited by 86 publications

(18 citation statements)

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“…The data from the literature review show that the outcome of the PTR in patients with advanced NSCLC differs considerably among radiotherapy departments: the mean survival time of these patients ranges from 4 to nearly 12 months, the 1-year survival rate varies between 14% and 48%, 2-year and 3-year survival rates-between 3% and 17%, and between 2% and 8%, respectively [3,5,7,9,[11][12][13][14][15][16]19,21,[23][24][25][26][27][28][29][30][31][32][33]. These differences result mainly from different characteristics of the presented groups.…”

Section: Discussionmentioning

confidence: 99%

Palliative thoracic radiotherapy in non-small cell lung cancer. An analysis of 1250 patients. Palliation of symptoms, tolerance and toxicity

et al. 2011

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Section: Discussionmentioning

confidence: 99%

Palliative thoracic radiotherapy in non-small cell lung cancer. An analysis of 1250 patients. Palliation of symptoms, tolerance and toxicity

et al. 2011

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“…Radiotherapy is often used of the palliation of respiratory systems and pain in patients with inoperable non-small cell lung cancer (NSCLC) but published data relating to treatment benefit are based on retrospective physician assessments of individual symptoms rather than on prospective patient self-assessments (Deeley et al, 1967;Durrant et al, 1971;Slawson et al, 1979;Simpson et al, 1985).…”

mentioning

confidence: 99%

Palliation and life quality in lung cancer; how good are clinicians at judging treatment outcome?

Regan

Yarnold²,

Jones³

et al. 1991

Br J Cancer

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Summary A recent trial by the MRC Lung Cancer Working Party used physician assessments to compare two palliative schedules of radiotherapy in lung cancer. A prospective study has been undertaken on a subset of these trial patients to see how physician assessments of symptomatic relief and general condition correlate with patient perception of therapeutic response. In 40 patients followed up monthly from presentation until close to death, good agreement was found between doctors and patients on change in specific physical symptoms and overall physical condition. Doctors were poor judges of life quality at presentation but appeared able to identify relative improvement or deterioration in overall quality of life. In conclusion, physician assessments may constitute valid end-points for radiotherapy trials comparing palliative schedules in lung cancer.

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“…While radiotherapy has proven highly effective in haemoptysis management, it does only resolve atelectasis in 23-54% of cases [6,110], and that is only as a delayed outcome (median 24 days). This suggests that some benefit could be gained by prior local treatment [7].…”

Section: Debulking and Radiotherapymentioning

confidence: 99%

Integration of interventional bronchoscopy in the management of lung cancer

et al. 2015

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Tracheal or bronchial proximal stenoses occur as complications in 20-30% of lung cancers, resulting in a dramatic alteration in quality of life and poor prognosis. Bronchoscopic management of these obstructions is based on what are known as "thermal" techniques for intraluminal stenosis and/or placement of tracheal or bronchial prostheses for extrinsic compressions, leading to rapid symptom palliation in the vast majority of patients. This invasive treatment should only be used in cases of symptomatic obstructions and in the presence of viable bronchial tree and downstream parenchyma.This review aims to clarify 1) the available methods for assessing the characteristics of stenoses before treatment, 2) the various techniques available including their preferred indications, outcomes and complications, and 3) the integration of interventional bronchoscopy in the multidisciplinary management of proximal bronchial cancers and its synergistic effects with the other specific treatments (surgery, radiotherapy or chemotherapy). @ERSpublications Central airway obstruction is a severe complication of lung cancer that can be managed by interventional bronchoscopy http://ow.ly/OdAhF

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Radiation Therapy in Bronchogenic Carcinoma

Cited by 86 publications

References 0 publications

Palliative thoracic radiotherapy in non-small cell lung cancer. An analysis of 1250 patients. Palliation of symptoms, tolerance and toxicity

Palliative thoracic radiotherapy in non-small cell lung cancer. An analysis of 1250 patients. Palliation of symptoms, tolerance and toxicity

Palliation and life quality in lung cancer; how good are clinicians at judging treatment outcome?

Integration of interventional bronchoscopy in the management of lung cancer

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