Radiation Treatment of Glioma of the Brain

Hyslop, George H.; Lenz, Maurice

doi:10.1097/00000441-192807000-00004

Cited by 10 publications

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“…In contrast, there is no general agreement on the use of radiation for patients with a benign astrocytoma, mixed glioma or oligodendroglioma. After more than 60 years' use of radiotherapy for gliomas, there are no results from prospective randomized studies (39,40). Postirradiation necrosis is one of the potentially lethal side effects and difficult to diagnose (41).…”

Section: Discussionmentioning

confidence: 99%

Therapy and survival of adult patients with intracranial glioma in a defined population

Kallio

2009

Acta Neurologica Scandinavica

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During the 3 years 1978–1980 146 adult patients with intracranial glioma were diagnosed in the Province of Uusimaa in southern Finland. The median survival of all patients was 15 months, of glioblastoma (n = 41) 5.1 months, of anaplastic astrocytoma (n = 29) 12.4 months, of benign grade I–II astrocytoma (n = 30) 93.5 months, of other glioma 82.9 months (n = 27), and of probable glioma 9.8 months (n = 19); 22 patients are still alive 8.9–11.9 years after diagnosis. The patients who were 15–44 years of age at the time of diagnosis survived 75.4 months in the median (n = 58), 45–64 years 10.5 months (n = 61) and 65 years or older 4.8 months (n = 27); 96 patients were operated, 89 received radiotherapy and 34 chemotherapy. According to the proportional hazards’model, follow‐up time, age and histological type of tumor were statistically highly significant in explaining differences in survival.

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Section: Discussionmentioning

confidence: 99%

Therapy and survival of adult patients with intracranial glioma in a defined population

Kallio

2009

Acta Neurologica Scandinavica

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“…The Al-Si spinel analyzed by Weiss et al is different from the g-Al 2 O 3 spinel because its lattice constant is 0.002 nm lower owing to the replacement of Al-ions by smaller Si-ions present in the cubic g-Al 2 O 3 spinel structure [215]. However, other researchers have supported the crystallization of g-Al 2 O 3 as the cause of the exothermic peak near 100 C [216][217][218][219][220][221]. There are two other exothermic peaks due to the crystallization of primary mullite and formation of cristobalite from amorphous silica that occur at 1,150 and 1,250 C respectively.…”

Section: Formation Of Mullite In Kaolinite Claysmentioning

confidence: 94%

Abrasive Tools and Bonding Systems

Jackson

Hitchiner²

2010

Machining With Abrasives

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The manufacture of high performance grinding wheels is heavily dependent upon the selecting the correct abrasive grain in terms of cutting ability, fracturing ability and the shape of the grain that controls metal removal rate, dressing interval, coolant delivery to the wheel-workpiece interface and chip evacuation. This chapter explains the recent developments in abrasive grains and bonding systems and should allow the reader to better select the correct abrasive grain and bonding system to economically machine materials.

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The treatment of cerebral tumours with radium

Ross¹

1931

Journal of British Surgery

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THE treatment of intracranial tumours by any method a t present conceived presents certain problems peculiar t o this field of surgery. There are difliculties of diagnosis, both anatomical and pathological ; difficulties of access ; and complications which arise from sudden changes in tension within the dural capsule, with resultant alterations in the circulation and damage t o the cerebral tissue. Gradually these problems havc bcen defined and tackled, and modifications in technique have been introduced to improve the methods of approach t o the brain, to obviate dangerous changes in intracranial tension, to reduce the risk of infection to the minimum, and to control haemorrhage. The recent adaptation of electrosurgical methods, the exact value of which is a t present difficult t o estimate, has been acclaimed the most notable advance in surgery since the introduction of antiseptics.Technical advances have led t o fresh discoveries in regard to the pathology of brain turnours, and have rendered possible and successful procedures which before the beginning of the present century would have proved too hazardous. This applies especially to the treatment of encapsulated tumours, but in the case of the gliomas it must be confessed that attempted removal, although carrying a much lower immediate mortality-rate than formerly, gives but a small chance of ultimate cure. Seeing that, if pituitary tumours be excluded, the glioma group constitutes over 70 per cent of the primary brain tumours verified by operation, the outlook is rather discouraging, and the hope has been expressed that radiotherapy might succeed where surgery has failed. The present studies have been undertaken t o try t o discover how far this hope is justifiable. The investigation is confined to the glioma group, though there are many recorded observations in regard to irradiation of endotheliomas, pituitary tumours, and neuroiibromas. PATHOLOGICAL CONSIDERATIONS.In order to understand the problem of the gliomas it is necessary t o make a brief reference t o their pathology. Of the many criteria which indicate the malignancy of a tumour, the most important is the character of the neoplastic cells, and especially the degree to which they are differentiated. The more embryonic and undifferentiated the cells, the more active is the growth and the more malignant the tumour ; and there is evidence that the

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Radiation Treatment of Glioma of the Brain

Cited by 10 publications

References 0 publications

Therapy and survival of adult patients with intracranial glioma in a defined population

Therapy and survival of adult patients with intracranial glioma in a defined population

Abrasive Tools and Bonding Systems

The treatment of cerebral tumours with radium

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