Radiative heating of superficial human tissues with the use of water-filtered infrared-A radiation: A computational modeling

Dombrovsky, Leonid A.; Timchenko, Victoria; Pathak, Chinmay; Piazena, Helmut; Müller, W.; Jackson, Michael

doi:10.1016/j.ijheatmasstransfer.2015.01.133

Cited by 40 publications

(25 citation statements)

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“…The programme provides a real-time control of the wIRA radiation unit by switching off and on in a defined range of maximum temperature (42-43 C) [17,19]. Treatment data were documented and stored.…”

Section: Thermographymentioning

confidence: 99%

Hypofractionated re-irradiation of large-sized recurrent breast cancer with thermography-controlled, contact-free water-filtered infra-red-A hyperthermia: a retrospective study of 73 patients

Notter

Piazena

Vaupel

2016

International Journal of Hyperthermia

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Purpose: Evaluation of the efficacy and toxicity of a new setup of thermographically controlled waterfiltered infra-red-A (wIRA) superficial hyperthermia (HT) combined with hypofractionated re-irradiation (re-RT) to treat large-sized breast cancer recurrences. Methods: Records of 73 heavily pre-irradiated patients with 103 treatment regions, treated from September 2009 to July 2015 were retrospectively analysed. Sixty-four patients with macroscopic disease were treated with 94 regions including 46 patients with lymphangiosis carcinomatosa. Hypofractionated RT consisted of 4 Gy once per week up to a total dose of 20 Gy delivered within 1-4 min after wIRA-HT. Heating of tumour nodules and diffusely spreading cancer lesions was performed under real-time thermographic temperature monitoring, maintaining the maximum skin temperature in the ROI between 42 C and 43 C, achieving intratumoural temperatures up to a depth of 2 cm between 39.5 C and 42 C. Seventeen patients received re-re-irradiation (re-re-RT) using the same HT/RT-treatment schedule. Results: Response rates in patients with macroscopic disease: 61% CR, 33% PR, 5% NC and 1% PD. Local control throughout life time after CR of macroscopic disease: 59%. All nine patients with microscopic disease had CR and local control throughout lifetime. Only grade 1 toxicities were observed. Conclusions: Application of thermographically controlled wIRA-HT combined with extremely low-dose re-irradiation provides good local control throughout lifetime of heavily pre-treated breast cancer recurrences. The twin wIRA radiator provides a sufficiently homogeneous heat deposition for the treatment of larger areas. The time lag between HT and re-RT is substantially reduced. The possibility of rere-RT opens new therapeutic options for the future. ARTICLE HISTORY

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Section: Thermographymentioning

confidence: 99%

Hypofractionated re-irradiation of large-sized recurrent breast cancer with thermography-controlled, contact-free water-filtered infra-red-A hyperthermia: a retrospective study of 73 patients

Notter

Piazena

Vaupel

2016

International Journal of Hyperthermia

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“…Note that a similar approach based on a set of 1-D solutions in the case of relatively small 2-D effects has been recently used in radiative transfer calculations [33].…”

Section: Radiative Transfer Modelmentioning

confidence: 99%

A simplified model for the shielding of fire thermal radiation by water mists

Dombrovsky

Dembele

Wen

2016

International Journal of Heat and Mass Transfer

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A solution for the complete problem of attenuation of fire radiation by water mist is presented. This solution is based on simplified approaches for the spectral radiative properties of water droplets, the radiative transfer in the absorbing and scattering mist, and transient heat transfer taking into account partial evaporation of water mist. A computational study of the conventional model problem indicates the role of the main parameters and enables one to formulate some recommendations to optimize possible engineering solutions. The method developed is also applied to more realistic case study of a real fire. It is suggested to decrease the size of supplied water droplets with the distance from the irradiated surface of the mist layer. The advantage of this engineering solution is confirmed by numerical calculations. Potential possibility of microwave monitoring of water mist parameters is analyzed on the basis of Mie theory calculations.

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“…It is important that 1-D problems can be solved with sufficient accuracy using simple differential approximation without any additional computing overheads. Note that a similar approach based on a set of 1-D solutions in the case of relatively small 2-D effects has been recently used in (Dombrovsky et al, 2015(Dombrovsky et al, , 2016b.…”

Section: Radiative Transfer Modelmentioning

confidence: 99%

Shielding of Fire Radiation With the Use of Multi-Layered Water Mist Curtains: Preliminary Estimates

Dombrovsky

Dembele

Wen

2016

Comput Thermal Scien

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Copies of full items can be used for personal research or study, educational, or not-for-profit purposes without prior permission or charge. Provided that the authors, title and full bibliographic details are credited, a hyperlink and/or URL is given for the original metadata page and the content is not changed in any way. Publisher's statement:Published version : http://www.dl.begellhouse.com/journals/648192910890cd0e,1e6659ad3a62cac6,38f69f0e2 e9039e0.html A note on versions:The version presented here may differ from the published version or, version of record, if you wish to cite this item you are advised to consult the publisher's version. Please see the 'permanent WRAP URL' above for details on accessing the published version and note that access may require a subscription.For more information, please contact the WRAP Team at: wrap@warwick.ac.uk SHIELDING OF FIRE RADIATION WITH THE USE OF MULTI-LAYERED WATER MIST CURTAINS: PRELIMINARY ESTIMATES

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Radiative heating of superficial human tissues with the use of water-filtered infrared-A radiation: A computational modeling

Cited by 40 publications

References 39 publications

Hypofractionated re-irradiation of large-sized recurrent breast cancer with thermography-controlled, contact-free water-filtered infra-red-A hyperthermia: a retrospective study of 73 patients

Hypofractionated re-irradiation of large-sized recurrent breast cancer with thermography-controlled, contact-free water-filtered infra-red-A hyperthermia: a retrospective study of 73 patients

A simplified model for the shielding of fire thermal radiation by water mists

Shielding of Fire Radiation With the Use of Multi-Layered Water Mist Curtains: Preliminary Estimates

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