Radical scavenging and antioxidant effects of Matricaria chamomilla polyphenolic–polysaccharide conjugates

Kołodziejczyk-Czepas, Joanna; Bijak, Michał; Saluk‐Bijak, Joanna; Ponczek, Michał B.; Żbikowska, Halina Małgorzata; Nowak, Paweł; Tsirigotis-Maniecka, Marta; Pawlaczyk, Izabela

doi:10.1016/j.ijbiomac.2014.09.032

Cited by 59 publications

(33 citation statements)

References 39 publications

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“…However, herbs and spices used for culinary purposes also represent an excellent, source of phytochemicals [12, 13]. Antioxidant and anti-inflammatory activities have been reported in vitro and in animal models for ginger ( Zingiber officinale ) [14], milk thistle ( Silybum marianum ) [15], hawthorn ( Crataegus monogyna ) [16, 17], passion flower ( Passiflora edulis ) [18] and chamomile ( Matricaria chamomilla ) [19, 20]. Therefore the health benefits of plant food-based diets could be related to both integrated antioxidant and anti-inflammatory mechanisms exerted by a wide array of phytochemicals present in fruit, vegetables, herbs and spices [21-24].…”

Section: Introductionmentioning

confidence: 99%

Functional Foods for Health: The Interrelated Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables, Herbs, Spices and Cocoa in Humans

Serafini

Peluso²

2017

CPD

195

112

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The health benefits of plant food-based diets could be related to both integrated antioxidant and anti-inflammatory mechanisms exerted by a wide array of phytochemicals present in fruit, vegetables, herbs and spices. Therefore, there is mounting interest in identifying foods, food extracts and phytochemical formulations from plant sources which are able to efficiently modulate oxidative and inflammatory stress to prevent diet-related diseases. This paper reviews available evidence about the effect of supplementation with selected fruits, vegetables, herbs, spices and their extracts or galenic formulation on combined markers of redox and inflammatory status in humans.

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Section: Introductionmentioning

confidence: 99%

Functional Foods for Health: The Interrelated Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables, Herbs, Spices and Cocoa in Humans

Serafini

Peluso²

2017

CPD

195

112

View full text Add to dashboard Cite

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“…Its pharmacological properties include antiseptic, healing, anti‐inflammatory, sedative and antispasmodic activities (Mericli, ). As a rich source of flavonoids and phenolic compounds, MC is of great antioxidant effect in neutralising free radicals (Gardiner, ; Kolodziejczyk‐Czepas et al, ; Rabiei, Moghtadaei, Mokhtari, & Rafieian‐Kopaei, ; Ranpariya, Parmar, Sheth, & Chandrashekhar, ).…”

Section: Introductionmentioning

confidence: 99%

The effect of hydroethanolic extract of Matricaria chamomilla on the reproductive system of male rats exposed to formaldehyde

et al. 2019

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Formaldehyde is a common agent in our surrounding environment and can adversely affect the male reproductive system. In this study, the effectiveness of Matricaria chamomilla (MC) extract as an antioxidant was investigated in rats treated with formaldehyde. Thirty‐two male Wistar rats were randomly divided into six groups: F (10 mg/kg formaldehyde), M200 (200 mg/kg MC extract), M500 (500 mg/kg MC extract), FM200 (10 mg/kg formaldehyde and 200 mg/kg MC extract), FM500 (10 mg/kg formaldehyde and 500 mg/kg MC extract) and control group (0.9% normal saline). Formaldehyde and MC extract were administered daily for 30 consecutive days via intraperitoneal injection. Hormonal status, sperm parameters, testis tissue histology, germinal cells apoptosis and stereological analyses of testis tissue were investigated. Testosterone and LH levels were significantly increased in FM200, FM500, F200 and F500 groups compared to F group (p ≤ 0.05). Sperm count, motility and viability were significantly enhanced in FM200, FM500, F200 and F500 groups compared to F group (p ≤ 0.05). A decrease in the number of apoptotic germ cells in FM200, FM500, M200 and M500 groups (p ≤ 0.05) was evident. In particular, the MC extract in dose 500 mg/kg is seen to reduce the adverse effects of formaldehyde on the reproductive system of male rats.

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“…These pharmacological properties suggest that the plant might be a valuable therapeutic option for the prophylaxis and treatment of various diseases, including inflammation, ulcers, sedation, hemorrhoids, cough, stomach ache, pharyngitis, and rheumatic pain [14]. Previous phytochemical investigations on M. chamomilla have led to the isolation of essential oil, flavonoids, terpenoids, and coumarins [15–19]. Among these chemical compositions, flavonoids are the main active constituents present in the plant, which exhibited anxiolytic and antidepressant activity [20, 21].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination and Pharmacokinetic Study of Quercetin, Luteolin, and Apigenin in Rat Plasma after Oral Administration of Matricaria chamomilla L. Extract by HPLC‐UV

Dong

Wei

Yin

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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A simple and sensitive HPLC-UV method has been developed for the simultaneous determination of quercetin, luteolin, and apigenin in rat plasma after oral administration of Matricaria chamomilla L. extract. The flow rate was set at 1.0 ml/min and the detection wavelength was kept at 350 nm. The calibration curves were linear in the range of 0.11–11.36 μg/ml for quercetin, 0.11–11.20 μg/ml for luteolin, and 0.11–10.60 μg/ml for apigenin, respectively. The intraday and interday precisions (RSD) were less than 8.32 and 8.81%, respectively. The lower limits of quantification (LLOQ) of the three compounds were 0.11 μg/ml. The mean recoveries for quercetin, luteolin, and apigenin were 99.11, 95.62, and 95.21%, respectively. Stability studies demonstrated that the three compounds were stable in the preparation and analytical process. The maximum plasma concentration (Cmax) was 0.29 ± 0.06, 3.04 ± 0.60, and 0.42 ± 0.10 μg/ml, respectively. The time to reach the maximum plasma concentration (Tmax) was 0.79 ± 0.25, 0.42 ± 0.09, and 0.51 ± 0.13 h, respectively. The validated method was successfully applied to investigate the pharmacokinetics study of quercetin, luteolin, and apigenin in rat plasma after oral administration of M. chamomilla extract.

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Radical scavenging and antioxidant effects of Matricaria chamomilla polyphenolic–polysaccharide conjugates

Cited by 59 publications

References 39 publications

Functional Foods for Health: The Interrelated Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables, Herbs, Spices and Cocoa in Humans

Functional Foods for Health: The Interrelated Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables, Herbs, Spices and Cocoa in Humans

The effect of hydroethanolic extract of Matricaria chamomilla on the reproductive system of male rats exposed to formaldehyde

Simultaneous Determination and Pharmacokinetic Study of Quercetin, Luteolin, and Apigenin in Rat Plasma after Oral Administration of Matricaria chamomilla L. Extract by HPLC‐UV

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