Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors

Abstract

Background: Recent developments in radiotherapeutic technology have resulted in a new approach to treating patients with localized lung cancer. We report preliminary clinical outcomes using stereotactic radiosurgery with real-time tumor motion tracking to treat small peripheral lung tumors.

Stereotactic body radiotherapy using real-time tumor tracking in octogenarians with non-small cell lung cancer

“…In these cases, bronchoscopic or intravascular marker placement provides a solution. Our complication rate after marker placement was acceptably low (5%) even when compared to complications in younger populations (16-28%) [40,41]. Treatment was also tolerated well by octogenarians despite treatment times of approximately 90 min.…”

Quality of Life After Stereotactic Radiotherapy for Stage I Non-Small-Cell Lung Cancer

“…Although the incidence of toxicity is not mentioned by Langendijk et al (15), the low incidence of toxicity after SRT may be the reason why symptom scores did not increase in our study. The risk of late toxicity is small (2-8%) after treating patients with SRT, as treatment volumes are generally small (4,12,16). On the other hand, the risk of toxicity after stereotactic irradiation of central tumors is not negligible (17) and may influence the patient's QoL.…”

Chest Wall Volume Receiving >30 Gy Predicts Risk of Severe Pain and/or Rib Fracture After Lung Stereotactic Body Radiotherapy

“…Multiple Phase I and II SBRT studies of the treatment of Stage I-II NSCLC have reported chest wall (CW) pain and/ or rib fracture as a part of the toxicity profile (6)(7)(8)(9). CW pain can be transient or can last several weeks or longer.…”