Radical versus supraomohyoid neck dissection in the treatment of squamous cell carcinoma of the inferior level of the mouth

Rapoport, Abrão; Ortellado, Daniel K.; Amar, Ali; Lehn, Carlos Neutzling; Dedivitis, Rogério Aparecido; Perez, Ricardo Salinas; Rodrigues, Helen Mara

doi:10.1016/s1808-8694(15)30124-5

Cited by 4 publications

(3 citation statements)

References 21 publications

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“…One of the characteristics of lips SCC is the extension of the tumor, which can manifest either towards the surface, in depth or in both directions. For instance, the occult metastases rates of a T2 stage lip cancer were reported in 15% to 35% of cases [17]. In such cases, elective neck dissection with excision of the primary tumor is the treatment of choice [18].…”

Section: Introductionmentioning

confidence: 99%

“…Computer tomography (CT), magnetic resonance imaging (MRI) and ultrasound can detect lymph nodes but not metastases. Therefore, sentinel lymph node biopsy (SLNB) is the most advisable option to diagnose metastases in the neck lymph nodes, especially in patients with N0 [17], and it may help in the treatment of these patients [19]. SLNB, as one of the procedures, is standard care for melanoma [20].…”

Section: Introductionmentioning

confidence: 99%

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Detection of Occult Metastases in Patients with T1 and T2 Stage Lower Lip Squamous Cell Carcinomas after Positive Lymphoscintigraphy

Loxha¹,

Stubljar²,

Jukić

et al. 2020

Diagnostics

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The aim of this study was to detect lower lip squamous cell carcinomas (SCC) that had metastasized to the lymph nodes and to evaluate if neck dissection was necessary for patients with T1 or T2-stage lip cancer after a sentinel lymph node biopsy (SLNB). The study was conducted as a prospective clinical study to detect occult neck metastases in patients with T1 or T2 stage SCC of the lower lip. Thirty-one patients were eligible and underwent echo-ultrasound, computer tomography, magnetic resonance and lymphoscintigraphy (LSG) as diagnostic procedures. LSG was performed on the same day as the surgical procedure, after intradermal injection of 37 Mbq Tc99m-Sn-colloid/mL at four peritumoral sites. In patients with positive LSG results, the sentinel lymph nodes were extracted surgically. The risk factors for cancer development were sun exposure and smoking. The highest accuracy for detecting lymph node enlargements was achieved with magnetic resonance imaging (MRI; 80.7%). LSG showed excellent sensitivity (100%) and negative predictive value (NPV; 100%). Overall, occult metastases were diagnosed with an SLNB in eight (25.8%) patients. According to the results, with great caution, we suggest that an SLNB is reasonable to initiate only for patients with positive sentinel nodes by positive LSG, to be used as a lower morbidity approach for selected patients with T1 and T2 stage cancers.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Detection of Occult Metastases in Patients with T1 and T2 Stage Lower Lip Squamous Cell Carcinomas after Positive Lymphoscintigraphy

Loxha¹,

Stubljar²,

Jukić

et al. 2020

Diagnostics

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“…A possible reason for the high surgical complication rates in this study is the kind of neck dissection performed. As shown in the supplementary section, the majority of the patients received a radical neck dissection instead of a modified radical neck dissection, which seems to be of sufficient oncologic safety in many clinical situations (Rapoport et al , ; Patel et al , ; Shepard et al , ).…”

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confidence: 99%